Results 61 to 70 of about 13,745 (204)

Glanzmann thrombasthenia [PDF]

open access: yes, 2006
Glanzmann thrombasthenia (GT) is a rare autosomal recessive bleeding syndrome affecting the megakaryocyte lineage and characterized by lack of platelet aggregation.
Alan T Nurden
core   +2 more sources

Pediatric cardiac surgery under cardiopulmonary bypass in factor VII deficiency

open access: yesThe Turkish Journal of Pediatrics, 2010
We present a case of an atrial septal defect repair under cardiopulmonary bypass in a child with factor VII deficiency. A four-year-old girl, with the diagnosis of secundum atrial septal defect, was referred to surgery. Coagulation tests showed an
Ozan Emiroğlu   +3 more
doaj  

Acquired Hemophilia A Presenting as Intramuscular Hematoma

open access: yesJournal of Investigative Medicine High Impact Case Reports, 2018
Acquired hemophilia A poses a clinical and diagnostic challenge. Although rare, it is still the most common acquired factor deficiency. We present a case of acquired hemophilia A diagnosed in a 71-year-old female who presented with a right thigh hematoma
Ghassan Al-Shbool MD, Anusha Vakiti MD
doaj   +1 more source

Successful Off-Label Use of Recombinant Factor VIIa and Coil Embolization in an Adolescent with Massive Hemoptysis Due to Invasive Pulmonary Aspergillosis

open access: yesTurkish Journal of Hematology, 2015
Invasive fungal infections have turned out to be a significant cause of morbidity and mortality in pediatric patients with malignant disorders. Massive hemoptysis, a rare complication of invasive pulmonary aspergillosis, may threaten the lives of ...
Dilek Gürlek Gökçebay   +4 more
doaj   +1 more source

Tissue factor in cardiovascular disease pathophysiology and pharmacological intervention [PDF]

open access: yes, 2010
Tissue factor (TF) is the major trigger of the coagulation cascade and thereby crucially involved in the maintenance of vascular hemostasis. By binding factor VIIa, the resulting TF:VIIa complex activates the coagulation factors IX and X ultimately ...
Holy, E W, Tanner, F C
core   +1 more source

The Role of Extracorporeal Membrane Oxygenation in Cardiopulmonary Dysfunction Due to Rheumatologic Diseases: A Systematic Review

open access: yesACR Open Rheumatology, Volume 8, Issue 4, April 2026.
Objective This systematic review documents the current status of extracorporeal membrane oxygenation (ECMO) use in patients with complications of rheumatologic diseases. Methods Following Preferred Reporting Items for Systematic Reviews and Meta Analyses 2020 guidelines, we conducted a systematic review of studies published from January 2019 to ...
Kari L. Falaas   +3 more
wiley   +1 more source

HEMOPHILIA INHIBITOR PATIENTS: THE USE OF RECOMBINANT FACTOR VIIa

open access: yesZdravniški Vestnik, 2004
Background. Recombinant factor VIIa can induce hemostasis and controls bleeding in surgery in hemophilia inhibitor patients and in other hemostatic disorders, e.g.
Dušan Andoljšek, Samo Zver
doaj  

Advances in the Treatment of Sensorineural Hearing Loss: From Traditional Therapies to Stem Cell and Gene Therapies

open access: yesAdvanced Sensor Research, Volume 5, Issue 4, April 2026.
Sensorineural hearing loss (SNHL) occurs in 1.5 billion globally, primary driven by damage of cochlear hair cells and spiral ganglion neurons. This review systematically examines current therapeutic strategies for sensorineural hearing loss, including traditional drug and physical therapies as well as emerging stem cell and gene therapies, providing a ...
Ruirui Chen   +3 more
wiley   +1 more source

Monitoring prohemostatic treatment in bleeding patients [PDF]

open access: yes, 2012
Acutely bleeding patients are commonly found in the trauma and major surgery scenarios. They require prompt and effective treatment to restore an adequate hemostatic pattern, to avoid serious and sometimes life-threatening complications.Different ...
Baryshnikova, E, Colella, D, Ranucci, M
core   +1 more source

Stent Thrombosis: A Narrative Review From Pathophysiology to Therapy

open access: yesClinical Cardiology, Volume 49, Issue 4, April 2026.
Stent thrombosis remains a life‐threatening complication of PCI driven by complex interactions between stent design, procedural factors, thrombogenic milieu, and inflammation. This review integrates pathophysiological mechanisms with contemporary and emerging therapeutic strategies, highlighting optimized PCI, tailored antithrombotic therapy, and novel
Emanuele Cecchi   +8 more
wiley   +1 more source

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