Results 181 to 190 of about 399,275 (342)

Optimization of a molecularly defined tuberculin formulation: recombinant fusion proteins and epitope surgery. [PDF]

open access: yesJ Clin Microbiol
Middleton S   +8 more
europepmc   +1 more source

Multitechnique study on a recombinantly producedBacillus haloduranslaccase and an S-layer/laccase fusion protein

open access: hybrid, 2011
Judith Ferner‐Ortner‐Bleckmann   +5 more
openalex   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

open access: yesAdvanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann   +26 more
wiley   +1 more source

Delta Opioid Receptors within the Cortico‐Thalamic Circuitry Underlie Hyperactivity Induced by High‐Dose Morphine

open access: yesAdvanced Science, EarlyView.
Morphine activates the excitatory cingulate cortex–intermediate rostrocaudal division of zona incerta (Cg‐ZIm) pathway to drive hyperlocomotion in mice. Inhibiting the Cg‐ZIm pathway attenuates both acute and chronic morphine‐induced hyperlocomotion, while its activation mimics morphine's motor effects.
Chun‐Yue Li   +13 more
wiley   +1 more source

Construction Of Recombinant E.Coli Expressing Fusion Protein To Produce 1,3-Propanediol

open access: green, 2011
Rosarin Rujananon   +6 more
openalex   +1 more source

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