Structural and antigenic characterization of Babesia Bovis HAP2 domains. [PDF]
Rahman SMR+5 more
europepmc +1 more source
An Off‐the‐Shelf Artificial Proregenerative Macrophage for Pressure Ulcer Treatment
Artificial macrophages (artM) by encapsulating M2 lysates into biodegradable PLGA microspheres and coated with macrophage membrane, are engineered as new therapeutics against skin pressure ulcer. In mouse models, the artM exhibited robust tissue repair through cell recruitment and microenvironment modulation, showing great therapeutic potential for ...
Qi Su+12 more
wiley +1 more source
Novel processes to obtain pneumococcal surface proteins for vaccines. [PDF]
Gonçalves VM.
europepmc +1 more source
Efficacy of Recombinant Bacille Calmette‐Guérin Vaccine Secreting Interleukin‐15/Antigen 85B Fusion Protein in Providing Protection againstMycobacterium tuberculosis [PDF]
Ce Tang+9 more
openalex +1 more source
This study reveals that M2‐EVs mitigate periodontitis‐induced bone resorption by modulating neutrophil fate. Single‐cell RNA sequencing identified an Anxa1hi neutrophil subpopulation with pro‐reparative properties. M2‐EVs disrupt neutrophil maturation, promoting this subpopulation through key reprogramming genes (Acvrl1, Fpr2). These findings highlight
Yufei Yao+7 more
wiley +1 more source
Creation of a highly stable direct electron transfer-type enzyme sensor by combining a hyperthermophilic dehydrogenase and natural electron mediator. [PDF]
Maeno M+4 more
europepmc +1 more source
Production of recombinant human erythropoietin/Fc fusion protein by genetically manipulated chickens [PDF]
Carlos A. Penno+3 more
openalex +1 more source
RACK7 Interacts with PRC2 Complex to Regulate Astrocyte Development
The study investigates the role of RACK7 in brain development using a conditional knockout mouse model. RACK7 deficiency results in developmental defects and abnormal astrocyte development by disrupting H3K27me3 chromatin binding. The underlying mechanism involves RACK7 interacting with the PRC2 complex to regulate the genomic localization of SUZ12 and
Fangfang Jiao+9 more
wiley +1 more source
Bacterial expression, purification and folding of exceptionally hydrophobic and essential protein: Surfactant Protein-B (SP-B). [PDF]
Asrat T, Jackman D, Booth V.
europepmc +1 more source