Results 221 to 230 of about 282,766 (336)

Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients [PDF]

, 2012
Jerry S. Powell, Neil C. Josephson, Doris Quon, Margaret V. Ragni, Gregory Cheng, Ella Li, Haiyan Jiang, Lian Li, Jennifer Dumont, Jaya Goyal, Xin Zhang, Jürg M. Sommer, Justin T. McCue, Margaret Barbetti, Alvin Luk, Glenn F. Pierce   +15 more
openalex   +1 more source

Microglial MS4A4A Protects against Epileptic Seizures in Alzheimer's Disease

Advanced Science, EarlyView.
This study has unveiled significant new insights into the role of MS4A4A in Alzheimer's disease‐related epilepsy, highlighting its impact on microglial phagocytosis, mitochondrial metabolism, and cytoskeleton, and demonstrating its therapeutic potential in epilepsy management.
Meng Jiang, Qingqing Li, Jianhui Chen, Ruochong Li, Jun Yao, Yong Hu, Haizheng Zhang, Lixin Cai, Maoguo Luo, Yu Sun, Wenwen Zeng   +10 more
wiley   +1 more source

Optimized expression of human interleukin-15 in <i>Nicotiana benthamiana</i> and <i>in vitro</i> assessment of its activity on human keratinocytes. [PDF]

Biotechnol Rep (Amst)
Charnsatabut C, Suwanchaikasem P, Rattanapisit K, Iksen I, Pongrakhananon V, Bulaon CJI, Phoolcharoen W.   +6 more
europepmc   +1 more source

A Phase‐Separated SR Protein Reprograms Host Pre‐mRNA Splicing to Enhance Disease Susceptibility

Advanced Science, EarlyView.
This study identifies SR30, a splicing factor, as a negative regulator of tomato immunity. During Phytophthora infestans infection, the elevated SR30 forms nuclear condensates to suppress the alternative splicing (AS) of defense‐related genes in a phase separation manner.
Dong Yan, Jie Huang, Fengqi Tian, Haidong Shu, Han Chen, Qian Peng, Hongwei Wu, Jianlong Zhao, Anireddy S. N. Reddy, Gang Li, Yuanchao Wang, Suomeng Dong   +11 more
wiley   +1 more source

Expression, Purification, and Refolding of Recombinant Fusion Protein hIL-2/mGM-CSF

, 2008
Qian Wen, Li Ma, Wei Luo, Mingqian Zhou, Xiaoning Wang   +4 more
openalex   +1 more source

Manipulating the Light Systemic Signal HY5 Greatly Improve Fruit Quality in Tomato

Advanced Science, EarlyView.
This study establishes that HY5, activated by low‐dose light, acts as a systemic signal to enhance tomato fruit quality by directly promoting carotenoid synthesis and sugar metabolism. These findings demonstrate HY5's mobility from leaves to fruits and its application potential through nighttime LED lighting, offering a practical strategy for crop ...
Jiachun Wang, Xiaomeng Li, Jiajia Li, Han Dong, Zhangjian Hu, Xiaojian Xia, Jingquan Yu, Yanhong Zhou   +7 more
wiley   +1 more source

Strategies to Enhance Protein Delivery. [PDF]

Langmuir
Zhu Y, Zhuang W, Cheng H.
europepmc   +1 more source

Recombinant protein of heptad-repeat HR212, a stable fusion inhibitor with potent anti-HIV action in vitro

, 2008
Wei Pang, Ruirui Wang, Liu‐Meng Yang, Chang‐Mei Liu, Po Tien, Yong‐Tang Zheng   +5 more
openalex   +1 more source

Genetically Engineered IL12/CSF1R‐Macrophage Membrane‐Liposome Hybrid Nanovesicles for NIR‐II Fluorescence Imaging‐Guided and Membrane‐Targeted Mild Photothermal‐Immunotherapy of Glioblastoma

Advanced Science, EarlyView.
A theranostic nanoplatform is formulated with NIR‐II emissive lipophilic cyanine dye IRC18 to intercalate into genetically engineered IL12/CSF1R‐macrophage membrane‐liposome hybrid nanovesicles, which assists to achieve blood–brain barrier crossing, glioblastoma targeting, NIR‐II fluorescence imaging, image‐guided membrane‐targeted mild photothermal ...
Pengfei Chen, Yue Liu, Haiyan Huang, Menglong Li, Hui Xie, Shubham Roy, Jingsi Gu, Jian Jin, Kai Deng, Lixin Du, Bing Guo   +10 more
wiley   +1 more source

Monoclonal antibody and B-cell epitope mapping of the VP7 protein in bluetongue virus. [PDF]

Virol J
Hu XB, Xu J, Zhang Y, Meng FH, Tian ZC, Guan GQ, Luo JX, Yin H, Du JZ.   +8 more
europepmc   +1 more source