Results 191 to 200 of about 6,805,202 (337)

Engineering Novel DNA Nanoarchitectures for Targeted Drug Delivery and Aptamer Mediated Apoptosis in Cancer Therapeutics

Advanced Functional Materials, EarlyView.
Designer DNA Architecture‐templated Drug Conjugates (DDA‐DCs) are comprised of a DNA nanomaterial decorated with multiple drug‐loaded DNA aptamers. DDA‐DCs use a combination of multiple aptamer types, each recognizing a different membrane protein to achieve precise targeting of cancer cells.
Abhisek Dwivedy, Dhyanesh Baskaran, Gaurav Sharma, Wei Hong, Dhanush Gandavadi, Abhichart Krissanaprasit, Joonsu Han, Yusheng Liu, Zack Zimmers, Tshepo Mafokwane, Ichrak Hayah, Neha Chauhan, Mengxi Zheng, Sherwood Yao, Keith Fraser, John S. Decker, Xiaohe Jin, Hua Wang, Adam D. Friedman, Xing Wang   +19 more
wiley   +1 more source

Biosynthesis and Genetic Encoding of Non-hydrolyzable Phosphoserine into Recombinant Proteins in Escherichia coli. [PDF]

Bio Protoc, 2023
Zhu P, Mehl RA, Cooley RB.
europepmc   +1 more source

Specific cellular immune response and neutralizing antibodies in goats immunized with native or recombinant envelope proteins derived from human T-lymphotropic virus type IIIB and in human immunodeficiency virus-infected men.

, 1987
Kai Krohn, W G Robey, Scott D. Putney, L O Arthur, P L Nara, Peter J. Fischinger, Robert C. Gallo, Flossie Wong‐Staal, Annamari Ranki   +8 more
openalex   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

Advanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Efficient Purification of Polyhistidine-Tagged Recombinant Proteins Using Functionalized Corundum Particles [PDF]

BioTech (Basel), 2023
Völzke JL, Smatty S, Döring S, Ewald S, Oelze M, Fratzke F, Flemig S, Konthur Z, Weller MG.   +8 more
europepmc   +2 more sources

Development of a new platform for secretory production of recombinant proteins in Corynebacterium glutamicum

Biotechnology and Bioengineering, 2016
S. Yim, Jae Woong Choi, Roojin Lee, Y. Lee, Se Hwa Lee, S. Kim, K. Jeong   +6 more
semanticscholar   +1 more source

Transmembrane Activation of Catalysis and Protein Refolding in Synthetic Cells by Enzymes and Nanozymes

Advanced Functional Materials, EarlyView.
Synthetic cells are engineered herein to respond to an external chemical messenger by the activation of intracellular catalysis. The chemical messenger molecules are catalytically generated by an extracellular enzyme or a mineral surface, whereas the intracellular catalysis emerges via direct enzyme activation or via protein refolding.
Dante G. Andersen, Andreas B. Pedersen, Mireia Casanovas Montasell, Søren Moesgaard, Anja Bille Bohn, Alexander N. Zelikin   +5 more
wiley   +1 more source

Purification and characterization of recombinant spinach acyl carrier protein I expressed in Escherichia coli.

, 1988
Daniel J. Guerra, Katarzyna Dziewanowska, John B. Ohlrogge, Phillip D. Beremand   +3 more
openalex   +1 more source

Mapping of B-cell epitopes on the outer membrane P2 porin protein of Haemophilus influenzae by using recombinant proteins and synthetic peptides [PDF]

, 1991
Diana Martı́n, Robert S. Munson, Susan Grass, P Chong, Josée Hamel, Gloria Zobrist, M. Klein, Bernard R. Brodeur   +7 more
openalex   +1 more source

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

Advanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires, Ezra Gordon, Heikyung Suh, Darrell J. Irvine, Paula T. Hammond   +4 more
wiley   +1 more source