Results 141 to 150 of about 138,518 (265)

Evaluation of the Association of Recombinant Proteins NanH and PknG from Corynebacterium pseudotuberculosis Using Different Adjuvants as a Recombinant Vaccine in Mice. [PDF]

Vaccines (Basel), 2023
Scholl NR, Silva MTO, Barbosa TN, de Pinho RB, Alves MSD, Portela RW, Azevedo VAC, Borsuk S.   +7 more
europepmc   +1 more source

Applications of chitosan derivatives as adjuvants for nanoparticle‐based vaccines: A comprehensive review

Smart Molecules, EarlyView.
This review highlights how chitosan derivatives enhance nanoparticle‐based vaccines through superior stability, mucoadhesion, and immune modulation. By triggering robust mucosal, humoral, and cellular responses, these biocompatible polymers serve as a transformative platform for next‐generation immunotherapeutics and safe and effective vaccine delivery
Sayantani Dasgupta, Susanta Paul, Swarupananda Mukherjee, Nilanjan Sarkar, Arvind Kumar, Amrita Chakraborty, Anannya Bose, Atanu Hazra, Mainak Chakraborty   +8 more
wiley   +1 more source

Development of a two-component recombinant vaccine for COVID-19. [PDF]

Front Immunol
Sun YS, Xu F, Zhu HP, Xia Y, Li QM, Luo YY, Lu HJ, Wu BB, Wang Z, Yao PP, Zhou Z.   +10 more
europepmc   +1 more source

Immune response of large yellow croaker Larimichthys crocea towards a recombinant vaccine candidate targeting the parasitic ciliate Cryptocaryon irritans. [PDF]

Aquac Int, 2023
Jiang S, Huang X, Li T, Zhang Y, Zhang J.   +4 more
europepmc   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Correction: An oral recombinant vaccine in dogs against Echinococcus granulosus, the causative agent of human hydatid disease: A pilot study. [PDF]

PLoS Negl Trop Dis
PLOS Neglected Tropical Diseases Editors.
europepmc   +1 more source

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

Smart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang, Haitao Xie, Guoqing Xiang, Yanhua Li, Changgui Tong, Hongyan Cui, Qixian Chen, Haidong Li, Yan Zhao   +8 more
wiley   +1 more source

Virus-like Particles Produced in Plants: A Promising Platform for Recombinant Vaccine Development. [PDF]

Plants (Basel)
Mardanova ES, Vasyagin EA, Ravin NV.
europepmc   +1 more source

Designing a Recombinant Vaccine against Providencia rettgeri Using Immunoinformatics Approach. [PDF]

Vaccines (Basel), 2022
Gul S, Ahmad S, Ullah A, Ismail S, Khurram M, Tahir Ul Qamar M, Hakami AR, Alkhathami AG, Alrumaihi F, Allemailem KS.   +9 more
europepmc   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source