Results 211 to 220 of about 138,518 (265)
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Current Opinion in Biotechnology, 1991
Research that may lead to the development of recombinant DNA-based vaccines has been conducted on a broad front. This has resulted in an increased understanding of immunological responsiveness to vaccines, the rational engineering of immunogens, and new means of delivering vaccines.
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Research that may lead to the development of recombinant DNA-based vaccines has been conducted on a broad front. This has resulted in an increased understanding of immunological responsiveness to vaccines, the rational engineering of immunogens, and new means of delivering vaccines.
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Recombinant vaccines against Leptospirosis
Human Vaccines, 2011Leptospirosis is an important neglected infectious disease that occurs in urban environments, as well as in rural regions worldwide. Rodents, the principal reservoir hosts of pathogenic Leptospira spp., and other infected animals shed the bacteria in their urine.
Odir A, Dellagostin +5 more
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The development of a recombinant Babesia vaccine
Veterinary Parasitology, 1992Crude extracts of Babesia bovis parasites were shown to induce levels of protection in susceptible cattle equivalent to that resulting from natural infection. The crude material was systematically fractionated and tested in numerous sequential vaccination/challenge experiments in adult cattle.
I.G. Wright +23 more
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Recombinant Therapeutic Protein Vaccines
Protein & Peptide Letters, 2013Recombinant technology has ushered in a new era for the pharmaceutical industry. Protein therapeutics, including plasma-derived products and antibodies obtained from the serum of infected patients, have been successfully adopted and utilized to treat various indications.
Satoshi, Ohtake, Tsutomu, Arakawa
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Recombination and flavivirus vaccines: a commentary
Vaccine, 2005A review article recently appeared in the Lancet by Seligman and Gould, in which the authors raise a safety concern for flavivirus vaccines based on possible recombination between wild-type viruses and live, attenuated vaccine viruses. Flaviviruses are small enveloped viruses with a single positive sense RNA genome containing a single long open reading
Monath, Thomas P. +16 more
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Nouveaux vaccins. Vaccins recombinants
Médecine et Maladies Infectieuses, 1987Resume Les progres en biotechnologie et les techniques de recombinaison du DNA permettent d'envisager la creation de vaccins et l'amelioration de l'efficacite et de la securite d'emploi des vaccins actuels : - Les vaccins a virus vivants de demain sont obtenus a partir de virus chimeres crees par genie genetique. Introduire un gene etranger dans l'
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Recombinant Proteins in Vaccine Development
2003The outer membrane of Neisseria meningitidis contains a variety of proteins with the potential for inclusion in new meningococcal vaccines (1). Studies on the vaccine potential of these proteins would be facilitated by the production of pure recombinant protein, free from other components of the Neisseria outer membrane.
M, Christodoulides +2 more
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Recombinant Vaccine Production: Production of a Recombinant CCHF MVA Vaccine
One of the key interventions against infection is immunization, including an increasing focus on development of vaccines against pathogenic bunyaviruses. Whilst different vaccine development approaches exist, recombinant viral vaccines have a strong safety record, are rapid to produce, are cost-effective, and have been demonstrated to be rolled out in ...Emma, Kennedy +2 more
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Recombinant vaccine delivery systems and encoded vaccines
Current Opinion in Immunology, 1994In addition to the introductory demonstrations of genetic immunization, the past year has brought significant advances in vaccine development. Particularly encouraging are live recombinant vaccines, studies demonstrating the potential to elicit both systemic and mucosal immune responses, more studies demonstrating immune protection in animal disease ...
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