Results 211 to 220 of about 108,676 (256)
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Current Opinion in Biotechnology, 1991
Research that may lead to the development of recombinant DNA-based vaccines has been conducted on a broad front. This has resulted in an increased understanding of immunological responsiveness to vaccines, the rational engineering of immunogens, and new means of delivering vaccines.
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Research that may lead to the development of recombinant DNA-based vaccines has been conducted on a broad front. This has resulted in an increased understanding of immunological responsiveness to vaccines, the rational engineering of immunogens, and new means of delivering vaccines.
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Recombinant BCG Vaccine Candidates
Current Molecular Medicine, 2007Given the variable protective efficacy provided by Mycobacterium bovis BCG (Bacillus Calmette-Guérin), there is a concerted effort worldwide to develop better vaccines that could be used to reduce the burden of tuberculosis. Recombinant BCG (rBCG) are vaccine candidates that offer some potential in this area.
Rogelio, Hernàndez-Pando +3 more
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Nouveaux vaccins. Vaccins recombinants
Médecine et Maladies Infectieuses, 1987Resume Les progres en biotechnologie et les techniques de recombinaison du DNA permettent d'envisager la creation de vaccins et l'amelioration de l'efficacite et de la securite d'emploi des vaccins actuels : - Les vaccins a virus vivants de demain sont obtenus a partir de virus chimeres crees par genie genetique. Introduire un gene etranger dans l'
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Recombinant vaccines for poultry
Vaccine, 1991The poultry industry relies on intensive farming to supply meat and eggs at relatively low cost. Many thousands of individuals are reared in enclosed houses which are left vacant for only short times between successive crops. Disease control is essential for the successful raising of poultry and this includes a need for cheap, effective vaccines ...
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Recombinant live virus vaccines
Immunology Letters, 1987Many successful vaccines are based on live attenuated viruses. An attractive idea is to genetically engineer these live attenuated vaccines so that they express protective antigens from other pathogens. Vaccinia virus, the smallpox vaccine, can be considered as the prototype for this sort of approach.
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Recombinant vaccine delivery systems and encoded vaccines
Current Opinion in Immunology, 1994In addition to the introductory demonstrations of genetic immunization, the past year has brought significant advances in vaccine development. Particularly encouraging are live recombinant vaccines, studies demonstrating the potential to elicit both systemic and mucosal immune responses, more studies demonstrating immune protection in animal disease ...
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1984
Of the many promises of the biotechnological revolution, none appear to offer more immediate application for improving the welfare of mankind than the biosynthesis by recombinant DNA (R-DNA) methods of vaccines for the diseases of humans and animals. Conventional vaccine development research for the production of both live and killed vaccines for human
Laurence A. Lasky, John F. Obijeski
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Of the many promises of the biotechnological revolution, none appear to offer more immediate application for improving the welfare of mankind than the biosynthesis by recombinant DNA (R-DNA) methods of vaccines for the diseases of humans and animals. Conventional vaccine development research for the production of both live and killed vaccines for human
Laurence A. Lasky, John F. Obijeski
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Recombinant viral vectors: Cancer vaccines
Advanced Drug Delivery Reviews, 2006To date cancer vaccines have yet to show efficacy in a phase III trial. However, the clinical benefit seen with monoclonal antibody mediated therapies (e.g., Herceptin) has provided proof of principle that immune responses directed against tumour-associated antigens could have therapeutic potential.
Richard, Harrop +2 more
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Recombinant vaccines against ovine footrot
Immunology & Cell Biology, 1993SummaryFor the past 20 years footrot vaccines have evolved from simple bacterins to highly specific recombinant DNA (rDNA) fimbrial vaccines. The development of these vaccines has left a trail of discoveries, challenges and solutions; these processes continue as we move closer to understanding the requirements of a footrot vaccine.
T J, O'Meara, J R, Egerton, H W, Raadsma
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Recombinant Vaccine Production: Production of a Recombinant CCHF MVA Vaccine
One of the key interventions against infection is immunization, including an increasing focus on development of vaccines against pathogenic bunyaviruses. Whilst different vaccine development approaches exist, recombinant viral vaccines have a strong safety record, are rapid to produce, are cost-effective, and have been demonstrated to be rolled out in ...Emma, Kennedy +2 more
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