Results 231 to 240 of about 1,656,346 (308)

Monoclonal antibodies target conserved S1^B epitopes across deltacoronaviruses to inhibit porcine deltacoronavirus infection. [PDF]

mBio
Zhou J, Jing R, Zhang M, Liu C, Li Y, Zhu H, Du W, Jongkaewwattana A, Bosch BJ, Peng G, He Q, Zhang M, Li W.   +12 more
europepmc   +1 more source

Uhrf1‐Mediated PKM2 Degradation via Ubiquitination Alleviates Inflammation and Pyroptosis in Inflammatory Bowel Disease

Advanced Science, EarlyView.
Uhrf1‐mediated PKM2 ubiquitination and degradation repressed the nuclear translocation of PKM2, and EPT served as a molecular glue capable of targeting the Uhrf1–PKM2 complex to alleviate the IBD course, suggesting that the Uhrf1–PKM2 axis was a previously unrecognized strategy for treating IBD.
Juan Zhang, Xin‐Rong Xu, Hui‐Lin Zhang, Qi‐Meng Zhu, Xin‐Yuan Li, Xi‐Peng Shang, Jing‐Hui Du, Christophe Morisseau, Feng Qiu, Cheng‐Peng Sun   +9 more
wiley   +1 more source

Longitudinal in vivo imaging reveals asynchronous, incomplete Nipah virus clearance with prolonged focal CNS involvement in IFNAR^-/- mice. [PDF]

Emerg Microbes Infect
Davies KA, Welch SR, Coleman-McCray JD, Ficarra G, Ritter JM, Sorvillo TE, Aida-Ficken V, Jain S, Albariño CG, Montgomery JM, Lo MK, Spiropoulou CF, Spengler JR.   +12 more
europepmc   +1 more source

Macrophage PARP7 Alleviates Septic Cardiomyopathy by Interacting With TBK1 and Suppressing TBK1‐Driven Inflammatory Response

Advanced Science, EarlyView.
In septic cardiomyopathy, PARP7 directly binds TBK1 and mediates its ADP‐ribosylation, thereby repressing TBK1‐driven proinflammatory signaling in macrophages. ABSTRACT Septic cardiomyopathy is a life‐threatening complication of sepsis, and an uncontrolled inflammatory response represents a key pathogenic mechanism. PARP7 negatively regulates the IFN‐I
Jibo Han, Lintao Wang, Xin Zhong, Shenggang Zhao, Huihui Xie, Xue Han, Liming Lin, Yiting Lyu, Ke Xu, Jiajun Xu, Xiaowen Shi   +10 more
wiley   +1 more source

Simultaneous detection of classic and natural recombinant myxoma virus strains in European brown hare population in West Hungary. [PDF]

Front Vet Sci
Kollár A, Kaszab E, Fehér E, Gál J, Tenk M.   +4 more
europepmc   +1 more source

THSD7A Exacerbates Atherosclerosis via Activation of Signaling Axis αvβ3/CEBPD/IL1A

Advanced Science, EarlyView.
THSD7A exerts pro‐inflammatory effects and exacerbates atherosclerosis. Mechanistically, THSD7A regulates endothelial cell inflammation and atherosclerosis by activating the αvβ3/CEBPD/IL1A signaling axis. THSD7A is not only a genetic marker but also a potential therapeutic target for coronary artery disease (CAD).
Jiankun Liu, Hongfei Liu, Yiqi Wan, Andong Wu, Jiayu Qiu, Xueting Gong, Ya Zhao, Yuanyuan Li, Bingbing Zhou, Yangyi Zheng, Fang Wu, Yuanzheng Zhu, Weixin Lv, Xueer Li, Qiang Yuan, Xiao‐Li Tian   +15 more
wiley   +1 more source

Advances in the application of recombinant herpesvirus-vectored vaccines in animal disease control. [PDF]

Front Microbiol
Guo J, Mei C, Sun X, Lin Q, Bu W, Xie S, Jiang B.   +6 more
europepmc   +1 more source

Expression of Orf Virus B2L Protein and Monoclonal Antibody Preparation. [PDF]

Microorganisms
Liu Y, Du J, Han F, Zhu K, Guo X.
europepmc   +1 more source

Metabolic Footprint of Drosophila S2 Cells: Findings During the Production of a Recombinant Rabies Virus Glycoprotein. [PDF]

Biotechnol J
Decarli MC, Dos Santos DP, Correia DM, de Azevedo AG, Suazo CAT, Moraes ÂM, Astray RM.   +6 more
europepmc   +1 more source

Comparative production of recombinant capripoxvirus in Vero cells using microcarrier- and macrocarrier-based dynamic cell culture systems under serum-free conditions. [PDF]

Appl Microbiol Biotechnol
Amanova Z, Sametova Z, Chervyakova O, Turyskeldy S, Kurmasheva A, Abitayev R, Ussembay A, Kondibayeva Z, Toktyrova D, Mazbayeva D, Zhugunissov K, Bulatov Y.   +11 more
europepmc   +1 more source