Results 11 to 20 of about 501,800 (253)

Genetic Recombination in Mycobacteria [PDF]

Journal of Bacteriology, 1973
Evidence for genetic recombination between Mycobacterium smegmatis strain Rabinowitchi (Rab) and strain Jucho or PM5 is presented. Backcrosses of recombinants by either parental strain indicated four different types of mating behavior, suggesting that the mycobacterial compatibilities are controlled by at least two ...
Tohru Tokunaga, Yasuo Mizuguchi, Kiyoko Suga   +2 more
openaire   +3 more sources

Recombination rate and selection strength in HIV intra-patient evolution [PDF]

, 2009
The evolutionary dynamics of HIV during the chronic phase of infection is driven by the host immune response and by selective pressures exerted through drug treatment.
A Eyre-Walker, A Jung, AE Jetzt, AR Templeton, AS Perelson, B Asquith, C Charpentier, C Kuiken, C Neuhauser, Christophe Fraser, CL Althaus, CTT Edwards, D Shriner, D Shriner, DJ Wilson, DN Levy, E Jones, E Simon-Loriere, G McVean, GA Bazykin, HY Lee, IM Rouzine, IM Rouzine, J Archer, J Chen, J Hunter, J Zhuang, JH Gillespie, L Chen, M Kimura, N Barton, N Barton, R Nielsen, R Shankarappa, RA Kaslow, RA Neher, RC Edgar, RC Griffiths, Richard A. Neher, RR Hudson, S Duffy, SA Seibert, SL Liu, T Leitner, T Nora, T Oliphant, Thomas Leitner, WJ Ewens, Y Yamaguchi   +48 more
core   +11 more sources

Genetic Recombination and Molecular Evolution [PDF]

Cold Spring Harbor Symposia on Quantitative Biology, 2009
Reduced rates of genetic recombination are often associated with reduced genetic variability and levels of adaptation. Several different evolutionary processes, collectively known as Hill-Robertson (HR) effects, have been proposed as causes of these correlates of recombination.
Charlesworth, B., Betancourt, A.J., Kaiser, V.B., Gordo, I.   +3 more
openaire   +4 more sources

Recombination and Self-Adaptation in Multi-objective Genetic Algorithms [PDF]

, 2004
This paper investigates the influence of recombination and self-adaptation in real-encoded Multi-Objective Genetic Algorithms (MOGAs). NSGA-II and SPEA2 are used as example to characterize the efficiency of MOGAs in relation to various recombination ...
Roboam, Xavier, Régnier, Jérémi, Sareni, Bruno   +2 more
core   +2 more sources

Recombination and Genetic Diversity

Trends in Computational and Applied Mathematics, 2012
In this paper we present a spatial stochastic model for genetic recombination, that answers if diversity is preserved in an infinite population of recombinating individuals distributed spatially. We show that, for finite times, recombination may maintain all the various potential different types, but when time grows infinitely, the diversity of ...
Coutinho, T. C., Silva, T.T.da, Toledo, G.L.   +2 more
openaire   +6 more sources

Genetic Recombination in Micromonospora [PDF]

Journal of Bacteriology, 1971
Biochemical mutants were obtained from Micromonospora chalcea, M. purpurea , and M. echinospora by using ultraviolet radiation or nitrosoguanidine. Crosses carried out between complementary nutritional mutants of the same species showed positive genetic interaction.
Maria Beretta, M. Polsinelli, Mirella Betti   +2 more
openaire   +3 more sources

Nonmutagenic carcinogens induce intrachromosomal recombination in dividing yeast cells. [PDF]

, 1993
A large number of animal and human carcinogens without apparent genotoxic activity exist (nonmutagenic carcinogens) that are difficult or impossible to detect with the currently used short-term tests.
Schiestl, RH
core   +2 more sources

SUMOylation of Rad52-Rad59 synergistically change the outcome of mitotic recombination [PDF]

, 2016
Homologous recombination (HR) is essential for maintenance of genome stability through double-strand break (DSB) repair, but at the same time HR can lead to loss of heterozygosity and uncontrolled recombination can be genotoxic.
Lisby, Michael, Silva, Sonia
core   +1 more source

The extent of error-prone replication-restart by homologous recombination is controlled by Exo1 and checkpoint proteins [PDF]

, 2014
Genetic instability, a hallmark of cancer, can occur when the replication machinery encounters a barrier. The intra-S phase checkpoint maintains stalled replication forks in a replication-competent configuration by phosphorylating replisome components ...
Ahn, Alabert, Bailis, Barlow, Bastia, Bester, Biswas, Boddy, Bolderson, Brown, Bähler, Carr, Carr, Casper, Cha, Chen, Cobb, Cobb, Codlin, Cotta-Ramusino, Dalgaard, De Piccoli, Durkin, El-Shemerly, Errico, Eydmann, Froget, Haghnazari, Halazonetis, Hartsuiker, Heichinger, Hu, Iraqui, Jia, Kai, Kaochar, Katou, Kolodner, Koundrioukoff, Krejci, Lambert, Lambert, Lambert, Lambert, Lambert, Lambert, Lee, Lindsay, Lisby, Lopes, Lucca, Maundrell, Meister, Mimitou, Miyabe, Miyabe, Mizuno, Mizuno, Moreau, Moreau, Moreno, Morin, Myung, Myung, Pandita, Raynard, Sabatinos, Segurado, Segurado, Smolka, Sogo, Stracker, Sun, Symington, Sørensen, Tercero, Tsubouchi, Watson, Zhu, Zou, Zubko   +80 more
core   +2 more sources

The effects of recombination rate on the distribution and abundance of transposable elements [PDF]

, 2008
Transposable elements (TEs) often accumulate in regions of the genome with suppressed recombination. But it is unclear whether this pattern reflects a reduction in the efficacy of selection against deleterious insertions or a relaxation of ectopic ...
Charlesworth, Brian, Dolgin, Elie S.
core   +2 more sources