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Recombineering and MAGE [PDF]

open access: possibleNature Reviews Methods Primers, 2021
Recombination-mediated genetic engineering, also known as recombineering, is the genomic incorporation of homologous single-stranded or double-stranded DNA into bacterial genomes. Recombineering and its derivative methods have radically improved genome engineering capabilities, perhaps none more so than multiplex automated genome engineering (MAGE ...
Michaela A. Jones   +16 more
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A Knowledge Recombination Perspective of Innovation: Review and New Research Directions

Journal of Management, 2021
A useful theoretical lens for understanding innovation in the strategy and entrepreneurship literatures is knowledge recombination. According to a recombination logic, innovations come about by recombining knowledge components, each of which is ...
Ting Xiao, Mona V. Makhija, S. Karim
semanticscholar   +1 more source

Recombinators, recombinases and recombination genes of yeasts [PDF]

open access: possibleCurrent Genetics, 1994
Genetic recombination in the nuclear, organellar, and plasmid genomes of eukaryotic organisms occurs during mitosis and meiosis. Mitotic recombination is an important mechanism for the repair of DNA damaged by ultraviolet light, ionizing radiation, and chemical agents (Friedberg et al. 1991).
Carlo V. Bruschi   +2 more
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Causes and Solutions of Recombination in Perovskite Solar Cells

Advances in Materials, 2018
Organic–inorganic hybrid perovskite materials are receiving increasing attention and becoming star materials on account of their unique and intriguing optical and electrical properties, such as high molar extinction coefficient, wide absorption spectrum,
Jiangzhao Chen, N. Park
semanticscholar   +1 more source

Recombination in yeast and the recombinant DNA technology

Genome, 1989
The development of methods to isolate eukaryotic genes, alter these genes in vitro and reintroduce them into the cell has had a major impact on the study of recombination in the yeast Saccharomyces cerevisiae. In this paper we discuss how recombinant DNA techniques have been employed in the study of recombination in yeast and the results that have ...
Martin Kupiec   +9 more
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Characterizing mutagenic effects of recombination through a sequence-level genetic map

Science, 2019
Human recombination and mutation mapped Genetic recombination is an essential process in generating genetic diversity. Recombination occurs both through the shuffling of maternal and paternal chromosomes and through mutations generated by resolution of ...
B. Halldórsson   +20 more
semanticscholar   +1 more source

Recombination: Meiotic Recombination in Fungi

1997
New combinations of genetic material are generated by the molecular process of genetic recombination. Recombination can affect all types of DNA: nuclear (mitosis and meiosis), organellar and plasmid DNA. Mitotic recombination is rare compared to meiotic recombination and appears to involve a less complex process (Esposito et al.
Heike Röhr, Ursula Kües, Ulf Stahl
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Recombination — Recombination in Higher Plants

1981
Recombination in higher plants is based on events which are coupled to the decisive steps of the sexual cycle, the fusion of the gametes and meiosis; which are introduced by experiments on asexual combinations, e.g., protoplast fusion, organelle transplantation and genetic engi­neering; and which occur in somatic cells, e.g., somatic crossing-over and ...
Reinhard Nehls, Horst Binding
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On Recombination

Artificial Life
Abstract The predominant explanations for including chromosomal recombination during meiosis are that it serves as a mechanism for repair or as a mechanism for increased adaptability. However, neither gives a clear immediate selective advantage to the reproducing organism itself.
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Recombination Pathways

2013
Homologous recombination is a complex process that has several important roles: repair of broken DNA, repair of disintegrated replication forks and generation of genetic diversity. Two independent recombination pathways, RecBCD and RecF(OR), operate in Escherichia coli. Both pathways are involved in the initial stages of recombination i.e.
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