Results 91 to 100 of about 228,630 (266)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Development Of A Collaborative Recommendation System Based on Singular Value Decomposition (SVD) on E-Commerce Data

open access: yesJournal of Applied Informatics and Computing
Recommendation systems (RS) are vital tools for mitigating information overload and data sparsity challenges in modern e-commerce platforms. This study focuses on developing and evaluating a Collaborative Filtering (CF) model utilizing Singular Value ...
Galih Mahalisa, Silvia Ratna, M. Muflih
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Online Resource-Aware Video Content Recommendation in Edge-Caches for Mobile Users

open access: yesIEEE Access
The coupling of content caching at the wireless network edge and video streaming recommendation systems has been thoroughly investigated to enhance the cache hit and improve the user quality of experience (QoE).
Ana Claudia Bastos Loureiro Moncao   +3 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

BitterMatch: recommendation systems for matching molecules with bitter taste receptors. [PDF]

open access: yesJ Cheminform, 2022
Margulis E   +5 more
europepmc   +1 more source

Design and Implementation of a Tourism Experimentation Platform for Context-Aware and Sustainable Recommendations

open access: yesApplied Sciences
The digitization of tourism has made numerous platforms available, but there remains a significant shortage of tools capable of promoting local events and activities.
Alessandro Abluton   +6 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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