Results 161 to 170 of about 22,424 (258)

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

Advanced Science, EarlyView.
A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang, Wenzhuo Yang, Wenting Cheng, Jing Zuo, Lin Pan, Sheng Zhong, Ren Geng, Yao Zhao, Zijian Chen, Canhua Huang, Yang Bai, Liyan Zhao, Yunqian Li   +12 more
wiley   +1 more source

A transfer RNA inosine modification drives genome-wide synonymous recoding across human commensal bacterial families. [PDF]

PNAS Nexus
Katanski CD, Pathirage C, Chang JC, Veseli I, Smith TJ, Foo M, Wu Y, Hou Y, Tran HAV, Rudzka D, Zhang W, Bayat Tork MA, Lolans K, Willis AD, Tang W, Eren AM, Federle MJ, Koutmou KS, Pan T.   +18 more
europepmc   +1 more source

Semi‐Artificial Photosynthesis Enables Light‐Driven Biomanufacturing in Non‐Photosynthetic Bacteria

Advanced Science, EarlyView.
A non‐invasive strategy exploits endogenous H2S metabolism in B. subtilis to drive in situ CdS biomineralization, enabling tight bio‐abiotic contact without genetic modification. Light harvested by the biomineralized nanoparticles powers NADPH regeneration, elevating 2’‐fucosyllactose and surfactin titres two‐ to three‐fold.
Jie Zheng, Anqi Tong, Wenxin Li, Meng Qiao, Yang Gu, Muhammad Sohail, Shan He, Sheng Yang, Xing Zhang   +8 more
wiley   +1 more source

An epigenetic mechanism of azole tolerance facilitates acquired antifungal resistance in <i>Aspergillus fumigatus</i>. [PDF]

mBio
Vellanki S, DeMichaelis N, Liao C, Stajich JE, Cramer RA.   +4 more
europepmc   +1 more source

Targeting Cannabinoid 1 Receptor in Macrophages Alleviates Psoriatic Skin Inflammation Through the AUF1–NLRP3 Axis

Advanced Science, EarlyView.
Macrophage CB1R emerges as a key driver of psoriatic inflammation by suppressing AUF1‐mediated post‐transcriptional control of NLRP3. CB1R inhibition restores AUF1‐dependent NLRP3 mRNA decay, restrains inflammasome activation, and alleviates psoriasis‐like inflammation.
Hongseo Choi, Sukyoung Han, Jinho Kim, Ji Hye Han, Eunsu Kim, Yeonjeong Heo, Minju Lee, Jooyoung Lee, Heerim You, Soyoun Lee, Su‐Hee Han, Ilrok Yoon, Sung Anjeon, Hyerim Kang, Seungyeon Ryu, Hyun‐Ji Park, Eunha Kim, Chul Hwan Bang, Ji Hyun Lee, Josephine M. Egan, Jung‐Woong Kim, Eun Kyung Lee, Wook Kim   +22 more
wiley   +1 more source

Biohybrid magnetic carrier robots for targeted bacteria release in ulcerative colitis. [PDF]

Mater Today Bio
Wang Z, Ding L, Zhang D, Misra S, Venkiteswaran VK.   +4 more
europepmc   +1 more source

Fully Recyclable Printed Magnetoresistive Sensors Covering Broad Operational Ranges for Sustainable Interactive Electronics

Advanced Electronic Materials, EarlyView.
This work presents a sustainable printing and recycling strategy for magnetic sensors designed for IoT applications. By combining solvent‐orthogonal binders with tailored magnetic fillers, the sensors achieve tunable sensitivity across low to high magnetic field ranges.
Rui Xu, Guannan Mu, Shirong Huang, Sebastian Lehmann, Gianaurelio Cuniberti, Kornelius Nielsch, Denys Makarov   +6 more
wiley   +1 more source

Proteomic characterization of <i>Tityus championi</i> venom and recombinant expression of its major neurotoxin. [PDF]

J Venom Anim Toxins Incl Trop Dis
Muñoz-Agames MDC, Salazar MH, Clement H, Hernández-Orihuela L, Hernández-Ortiz M, Encarnación-Guevara S, Cleghorn J, Acosta H, Corzo G.   +8 more
europepmc   +1 more source

Border harm and affective injustice: The politics of anger at the Melilla border, Spain

American Journal of Community Psychology, EarlyView.
Abstract This article examines protests in a detention center in Melilla, Spain—a site where structural violence intersects with the everyday harms of confinement. Adopting a justice and dignity‐centered perspective, we analyze grassroots forms of resistance emerging at the border. The study focuses on the protests of Tunisian migrants and explores the
Corina Tulbure
wiley   +1 more source

A conserved cargo recognition mechanism establishes TANGO1 as a selective extracellu lar matrix cargo receptor

Nüchel J, Accogli A, Lütke S, Titze S, Wilhelm S, Tauber M, Oehlert F, Koch M, Capra V, Maroofian R, Zamani M, Vinkšel Prah M, Heath KE, Bloch-Zupan A, Offiah AC, TANGO1 consortium, Plomann M, Eckes B, Krieg T, Kümmel D, Schiavinato A, Sengle G, Demetriades C.   +22 more
europepmc   +1 more source