Results 21 to 30 of about 22,424 (258)

Re-introducing the Cambridge Group Family Reconstitutions [PDF]

Historical Life Course Studies, 2020
English Population History from Family Reconstitution 1580–1837 was important both for its scope and its methodology. The volume was based on data from family reconstitutions of 26 parishes carefully selected to represent 250 years of English demographic history.
Alter, George, Newton, Gill, Oeppen, James   +2 more
openaire   +8 more sources

Spectratyping analysis of the islet-reactive T cell repertoire in diabetic NOD Igμ^null mice after polyclonal B cell reconstitution

Journal of Translational Medicine, 2011
Background Non Obese Diabetic mice lacking B cells (NOD.Igμnull mice) do not develop diabetes despite their susceptible background. Upon reconstitution of B cells using a chimera approach, animals start developing diabetes at 20 weeks of age.
Sercarz Eli E, Braciak Todd A, Sheng Huiming, Norori Patricia Y, Daneshjou Nazila, Vong Allen M, Gabaglia Claudia   +6 more
doaj   +1 more source

FAMILIAS RECONSTITUIDAS: PERCEPCIONES DE MADRES, HIJOS E HIJAS DESDE SUS DINÁMICAS RELACIONALES

Revista Latinoamericana de Estudios de Familia
Objective: This study explores the perceptions of mothers and biological children regarding relational dynamics within their reconstituted families, their processes of identification and family belonging, and seeks to contribute to their recognition and ...
Yamila Madrid-Salas, Mercedes Rodríguez-López, Verena Pérez-Redondo   +2 more
doaj   +1 more source

La constitution de ressources urbaines dans les parcours de familles migrantes à Mexico

EchoGéo, 2017
This paper aims to characterize urban resources in the context of Mexico City. Through six portraits of six women which migrated to Naucalpan, an industrial suburb of Mexico city, we expect to show how migrant families face the challenge of settling in ...
Aurélia Michel
doaj   +1 more source

Cleft lip and palate: evaluation of the psychological impact using the Rosenberg self-esteem scale [PDF]

Revista Brasileira de Cirurgia Plástica, 2018
Introduction: Cleft lip and palate is the most frequent malformation of the head region and affects more than 10 million people worldwide. This study aims at evaluating the self-esteem in patients with cleft lip and palate and comparing that with the ...
Alesandra Glaeser, Sady Selaimen da Costa, Marcus Vinicius Martins Collares   +2 more
doaj   +1 more source

Neue Familienformen. Herausforderungen für das Recht

Journal of Family Research, 2016
Family forms are subject to constant change. Apart from the rise in reconstituted families and children growing up in same-sex partnerships, artificial reproduction has led to particular challenges for law. The current legal situation does not correspond
Nina Dethloff
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source