Results 61 to 70 of about 349,767 (257)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The conquest and colonization of Mesoamerica by Spain during the period AD 1519-1821 forms part of a macroregional interaction network known as the modern or capitalist world system.
Rani T. Alexander
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
At the Hawk’s Well A Theoretical and Practical Study about the Music in the Play
William Butler Yeats (1865-1939) is a pillar of the so-called Irish Literary Revival. His work has influenced authors such as T. S. Eliot (1888-1965) and Samuel Beckett (1906-1989), among many others.
Maestro Marcello Amalfi
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The modern trends of development of the pipe and tube industry [PDF]
First the paper presents a review of steel production of the tubes in world: possible potencial is about 110 × 106 the tons (35 × 106 seamless tubes, rest welding tubes). In 2007. y.
YU. G. Gulyayev +4 more
doaj
Law, Urban Violence and Order: Cop Shows as a Brazilian TV Genre
A new type of Brazilian drama series has taken place on local TV - the cop shows. Although they are not popular as the telenovela (soap operas), definitively they came to stay. International channels like Fox and HBO are benefited by Tax Benefits Rule
Luiza Lusvarghi
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source

