Results 71 to 80 of about 349,767 (257)

Industrial ceramics in Spain

open access: yesBoletín de la Sociedad Española de Cerámica y Vidrio, 2000
The Spanish ceramic industry has experienced a amazing growth in the last four years. Such expansion has affected all sector, but has been particularly noteworthy in those directly related to construction: tiles. glazes, bricks and roof tiles.
Regueiro, M.   +3 more
doaj  

Optimization of Vehicle Routing with Pickup Based on Multibatch Production

open access: yesDiscrete Dynamics in Nature and Society, 2018
To reduce the inventory cost and ensure product quality while meeting the diverse demands of customers, manufacturers yield products in batches. However, the raw materials required for manufacturing need to be obtained from suppliers in advance, making ...
Hongtao Hu, Jiao Mo, Chengle Ma
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Correction to: Arthroscopic treatment of focal osteochondral lesions of the first metatarsophalangeal joint

open access: yesJournal of Orthopaedic Surgery and Research, 2019
This article [2] was published twice [1] due to a production error. The original article [1] should be considered the version of record and used for citation purposes.
Ersin Kuyucu   +4 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

INTEGRATION OF INFORMATIONAL COMPUTER TECHNOLOGIES SMK: AUTOMATION OF THE MAIN FUNCTIONS OF THE TECHNICAL CONTROL DEPARTMENT

open access: yesЛитьë и металлургия, 2010
It is shown that automation of some functions of control department allows to record defects, reclamations and failures of technology, to make the necessary reporting forms and quality certificates for production.
S. A. Pavlenko
doaj  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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