Results 31 to 40 of about 32,466 (303)

Early Archean origin of heterodimeric Photosystem I

open access: yesHeliyon, 2018
When and how oxygenic photosynthesis originated remains controversial. Wide uncertainties exist for the earliest detection of biogenic oxygen in the geochemical record or the origin of water oxidation in ancestral lineages of the phylum Cyanobacteria.
Tanai Cardona
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Concentration-Dependent Toxicity of Iron Oxide Nanoparticles Mediated by Increased Oxidative Stress [Retraction]

open access: yesInternational Journal of Nanomedicine, 2022
Naqvi S, Samim M, Abdin M, et al. Int J Nanomedicine. 2010;5:983–989. The Editor and Publisher of the International Journal of Nanomedicine wish to retract the published article.
Naqvi S   +7 more
doaj  

Stewardship of the evolving scholarly record: from the invisible hand to conscious coordination [PDF]

open access: yes, 2015
The scholarly record is increasingly digital and networked, while at the same time expanding in both the volume and diversity of the material it contains.
Constance Malpas, Brian Lavoie
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Prevention of digital music file duplication [PDF]

open access: yes, 2015
Current digital music file duplication software only detects the duplication of digital music file in the hard disk of a personal device [1, 2].This study develops a biologically inspired model for storing audio data (BiMSAD) to prevent duplication of ...
Hamzah, Hammuzamer Irwan   +2 more
core  

Oblivious transfer with access control: Realizing disjunction without duplication

open access: yes, 2010
Oblivious Transfer with Access Control (AC-OT) is a protocol which allows a user to obtain a database record with a credential satisfying the access policy of the record while the database server learns nothing about the record or the credential.
Huang, Q   +13 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Preparation, in vitro and in vivo Evaluation of Thermosensitive in situ Gel Loaded with Ibuprofen-Solid Lipid Nanoparticles for Rectal Delivery [Retraction]

open access: yesDrug Design, Development and Therapy, 2022
Huang CH, Hu PY, Wu QY, et al. Drug Des Devel Ther. 2022;16:1407‒1431. The Editor and Publisher of Drug Design, Development and Therapy wish to retract the published article.
Huang CH   +8 more
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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