Results 121 to 130 of about 378,041 (330)

Benefits of not smoking during pregnancy for non-Aboriginal women and their babies in New South Wales, Australia: a record linkage study

, 2021
Jillian A. Patterson, Aaron Cashmore, Sally J. Ioannides, Andrew Milat, Tanya Nippita, Jonathan Morris, Siranda Torvaldsen   +6 more
openalex   +2 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

ADGN: An Algorithm for Record Linkage Using Address, Date of Birth, Gender, and Name [PDF]

, 2017
Stephen Ansolabehere, Eitan Hersh
openalex   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

432 Reducing delays in the time to first-feed for babies with polyhydramnios: a quality improvement project at a UK district general hospital

BMJ Paediatrics Open, 2021
Igor Fierens, Catherine Taylor, Timothy Shields, Olatejumoye Knee, Antonia Katana   +4 more
doaj   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

438 Promoting safe sleeping in a neonatal unit

BMJ Paediatrics Open, 2021
Catherine Taylor, Amna Suliman, Martha Jones, Louise Mawby, Esmira Jafarova, Sarah Panjwani   +5 more
doaj   +1 more source

Multiple hospital organisational factors are associated with adverse patient outcomes post-hip fracture in England and Wales: the REDUCE record-linkage cohort study [PDF]

, 2022
Rita Patel, Andrew Judge, Antony Johansen, Elsa Marques, Jill Griffin, Marianne Bradshaw, Sarah Drew, Katie Whale, Tim Chesser, Xavier L Griffin, M K Javaid, Yoav Ben‐Shlomo, Celia L. Gregson   +12 more
openalex   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Multiple sclerosis after infectious mononucleosis: record linkage study [PDF]

, 2004
Michael J Goldacre, Clare J Wotton, Valerie Seagroatt, David Yeates   +3 more
openalex   +1 more source