Results 101 to 110 of about 3,332,803 (295)

Defect production in quench from current-carrying non-equilibrium state

open access: yes, 2016
We consider the defect production of a quantum system, initially prepared in a current-carrying non-equilibrium state, during its unitary driving through a quantum critical point. At low values of the initial current, the quantum Kibble-Zurek scaling for
Harris, Rosemary J., Karevski, Dragi
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Record values and the exponential distribution

open access: yesJournal of Applied Probability, 1981
Let X1, X2, · ·· be i.i.d. and Yk = max{X1, X2, · ··, Xk}. Then Xj is a record value of the sequence if Yj > Yj-1). Denoting record value times by Ln, n = 1, 2, ···, we prove that the independence of XLj − XLi and XLi with Lj > characterizes the exponential distribution.
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Do People Value Recorded Music? [PDF]

open access: yesCultural Sociology, 2019
How much do the majority of people value music, and can or should that level of value be reflected in music’s economic value? The dramatic decline in the economic value of recorded popular music in the 21st century has prompted much debate about music being ‘devalued’ and the perceived ‘value gap’ between music’s socio-cultural and economic values ...
openaire   +3 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

On Estimation of Reliability Functions using Record values from Proportional Hazard Rate Model

open access: yesAustrian Journal of Statistics, 2019
Two measures of reliability functions, namely R(t)=P(X>t) and P=P ...
Ajit Chaturvedi, Ananya Malhotra
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Statistical Properties and Applications of k-Record Values Based on the Generalized Lindley Distribution

open access: yesJournal of Probability and Statistics
This research explores the characteristics and uses of k-record values derived from the generalized Lindley distribution, an adaptable extension of the traditional Lindley distribution.
Maysam Abdulnabi Abdulhasan Al-Saedi   +3 more
doaj   +1 more source

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