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Pronóstico al año tras sufrir el debut de enfermedad cerebrovascular en pacientes de un hospital nacional de Lima, Perú

Revista Peruana de Medicina Experimental y Salud Pública
En Latinoamérica la información del pronóstico de pacientes con enfermedad cerebrovascular (ECV) es limitada. Por ello, se buscó determinar el pronóstico vital y funcional al año, de pacientes con debut de ECV.
C. Martín A Alvarado-Dulanto, María de los Ángeles Lazo, Javier D Loza-Herrera, Germán Málaga   +3 more
doaj  

Internal or External Training Load Metrics: Which Is Best for Tracking Autonomic Nervous System Recovery and Function in Collegiate American Football? [PDF]

J Funct Morphol Kinesiol, 2023
Renaghan E, Wittels HL, Wittels SH, Wishon MJ, Hecocks D, Wittels ED, Hendricks S, Girardi J, Lee SJ, McDonald SM, Feigenbaum LA.   +10 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

An Intensive Exercise Program Using a Technology-Enriched Rehabilitation Gym for the Recovery of Function in People With Chronic Stroke: Usability Study. [PDF]

JMIR Rehabil Assist Technol, 2023
Kerr A, Keogh M, Slachetka M, Grealy M, Rowe P.   +4 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

CD4+ T Cell Dependent B Cell Recovery and Function After Autologous Hematopoietic Stem Cell Transplantation. [PDF]

Front Immunol, 2021
Heck C, Steiner S, Kaebisch EM, Frentsch M, Wittenbecher F, Scheibenbogen C, Hanitsch LG, Nogai A, le Coutre P, Bullinger L, Blau IW, Na IK.   +11 more
europepmc   +1 more source

MSC derived EV loaded with miRNA‐22 inhibits the inflammatory response and nerve function recovery after spinal cord injury in rats [PDF]

, 2021
Yongjia Sheng, Xiaohong Zhou, Jin Wang, Heping Shen, Shasha Wu, Weiqun Guo, Yi Yang   +6 more
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Novel Influences of Sex and APOE Genotype on Spinal Plasticity and Recovery of Function after Spinal Cord Injury. [PDF]

eNeuro, 2021
Strattan LE, Britsch DRS, Calulot CM, Maggard RSJ, Abner EL, Johnson LA, Alilain WJ.   +6 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source