Results 91 to 100 of about 1,831,438 (310)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Differences in five kilometer time trial performance during the recovery period after an ultramarathon race

, 2013
Includes abstract.Includes bibliographical references.Athletes require an appropriate balance between training, competition stress and recovery to achieve maximal performance. Previous studies have shown that exercise induced muscle damage has a negative
Benney, Tamlyn
core  

Effect of cigarette smoke on gustatory sensitivity, evaluation of the deficit and of the recovery time-course after smoking cessation

, 2017
Introduction Study results have shown that chronic exposure to cigarette smoke affects the taste function in humans. However, neither the quantitative impact on taste sensitivity nor the time-course of taste recovery on stopping smoking have been ...
Hélène Sancho Garnier, Fabrice Chéruel, Marta Jarlier, Hélène Sancho-Garnier   +3 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Perceived justice in email service recovery

, 2007
This study adds to the limited research of service recovery in an online environment, drawing on data from Australia. It is perhaps the first non-US study of email service recovery as well as the first to apply a theoretical perspective - perceived ...
Neale, L.G., Murphy, J.
core  

Risk factors of acquired dysphagia in patients after posterior cranial fossa surgery

Huli yanjiu, 2023
ObjectiveTo investigate the status quo and risk factors of acquired dysphagia in patients after posterior cranial fossa surgery，and to provide reference for early intervention of dysphagia and optimization of postoperative rehabilitation.MethodsA total ...
QI Chunxia, ZHANG Yazhi, LI Chunlin, YANG Qin, LI Yueting, GAO Ting, DU Xiaoliang   +6 more
doaj  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Early Physical Therapy and EMS Interventions in Emergency Departments for Acute Musculoskeletal Injuries: Impact on Recovery Time and Hospital Throughput [PDF]

Journal of Medical and Life Science
Background: Acute musculoskeletal (MSK) injuries, including strains, sprains, and fractures, account for 20–30% of emergency department (ED) visits, contributing to overcrowding and prolonged hospital stays.
Sadiq Alwadani, Abdulaziz Al-Mutairi, Ahlam Alotaibi, Shrouq Albloushi, Abdulazeez Alrajeh, Mohammed Albalawi, Amid Albalawi   +6 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source