Results 51 to 60 of about 17,118,890 (293)

Social Protection and Disaster Recovery

, 2020
This note highlights the critical contribution that social protection can make to a broader disaster recovery effort by helping directly to disaster-affected households.
Global Facility for Disaster Reduction and Recovery
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Recovery of the Starting Times of Delayed Signals

IEEE Signal Processing Letters, 2018
We present a new method to locate the starting points in time of an arbitrary number of (damped) delayed signals. For a finite data sequence, the method permits to first locate the starting point of the component with the longest delay, and then --by iteration-- all the preceding ones.
Luca Perotti, Daniel Vrinceanu, Daniel Bessis   +2 more
openaire   +4 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Early Physical Therapy and EMS Interventions in Emergency Departments for Acute Musculoskeletal Injuries: Impact on Recovery Time and Hospital Throughput [PDF]

Journal of Medical and Life Science
Background: Acute musculoskeletal (MSK) injuries, including strains, sprains, and fractures, account for 20–30% of emergency department (ED) visits, contributing to overcrowding and prolonged hospital stays.
Sadiq Alwadani, Abdulaziz Al-Mutairi, Ahlam Alotaibi, Shrouq Albloushi, Abdulazeez Alrajeh, Mohammed Albalawi, Amid Albalawi   +6 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Accurate empathy of romantic partners increases pain ratings but promotes recovery

Psychology Research and Behavior Management, 2018
Binghai Sun,1 Lingyan Zhou,1 Weilong Xiao,1 Xiaoqian Zhao,1 Wenhai Zhang,1,2 Weijian Li1 1School of Teacher Education, Zhejiang Normal University, Jinhua 321004, China; 2Mental Health Center, Yancheng Institute of Technology, Yancheng 224051, China ...
Sun B, Zhou L, Xiao W, Zhao X, Zhang W, Li W   +5 more
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Evaluation of the Effectiveness of Eugenol and MS-222 as Anesthetics in Zebrafish in Repeated Exposures and Post-Anesthesia Behaviour

Animals
The increasing use of the zebrafish (Danio rerio) in scientific experiments has made it necessary to implement anesthesia protocols guaranteeing minimum pain and suffering for these animals and ensuring the reliability of the results obtained from their ...
Nahúm Ayala-Soldado, Rafael Mora-Medina, Ana María Molina-López, Antonio Jesús Lora-Benítez, Rosario Moyano-Salvago   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source