Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska +14 more
wiley +1 more source
Developing disability inclusive coaching principles within community recreational sport programming for children. [PDF]
O'Rourke RH +5 more
europepmc +1 more source
A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu +16 more
wiley +1 more source
Using old fields for new purposes: ecosystem service outcomes of restoring marginal agricultural land to forests. [PDF]
Destrempes C +6 more
europepmc +1 more source
Ultrasound‐Actuated Gene Editing in Human Kidney Organoids
Peptide‐stabilized nanoemulsions enable spatially controlled, ultrasound‐triggered delivery of gene‐editing proteins deep within human kidney organoid tissues. Focused acoustic pulses drive droplet vaporization, propelling cargo into target renal cells while preserving native tissue microarchitecture. This non‐viral platform improves both the depth and
Michael A. Miller +6 more
wiley +1 more source
Mental health placements for health and social care students: A realist synthesis. [PDF]
Rees CE +6 more
europepmc +1 more source
Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel +15 more
wiley +1 more source
Organizational culture and sport: a narrative review and proposed synthesis framework. [PDF]
Cairney J +6 more
europepmc +1 more source
Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma +11 more
wiley +1 more source
Examining the effect of authentic leadership and contextual performance on work engagement among employees working in sports organizations. [PDF]
İnce U +3 more
europepmc +1 more source

