Results 31 to 40 of about 1,287,280 (249)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Multi-Ideology Multi-Class Extremism Classification Using Deep Learning Techniques

IEEE Access, 2022
Social media is an integral part of today’s social communication. Social media platforms have a global reach with immense popularity among the young generation. This reach and influencing power of social media has attracted extremist and terrorist
Mayur Gaikwad, Swati Ahirrao, Ketan Kotecha, Ajith Abraham   +3 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

What HR Issues and Challenges are Addressed by Contemporary HR Professionals and Line Managers? A Survey Evidence from the Czech Republic

Economics and Culture
Succeeding in a changing business world means being familiar with emerging business trends, including issues and challenges related to human resources (HR).
Skýpalová Renata, Šikýř Martin, Vávrová Jana   +2 more
doaj   +1 more source

Sure you are ready? Gendered arguments in recruitment for high-status positions in male-dominated fields

Frontiers in Psychology, 2023
Recruitment contexts such as STEM professorships promote clearly defined selection criteria and objective assessment. We illuminate in these contexts, the subjective interpretation of seemingly objective criteria and gendered arguments in discussions of ...
Regina Dutz, Sylvia Hubner-Benz, Franziska Emmerling, Claudia Peus   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

CAREGIVERS OF MENTALLY ILL PATIENTS: ROLE OF COPING STYLE AND EMOTIONAL INTELLIGENCE

Pakistan Armed Forces Medical Journal, 2019
Objective: To explore the role of coping style and emotional intelligence of caregivers of mentally ill patients. Study Design: Present study was cross-sectional.
Ashar Saeed, Shoaib Kiani, Saira Javed
doaj  

Pratiques de recrutement et formes de discrimination des femmes diplômées – le cas du Chili

L'Ordinaire des Amériques, 2015
This paper analyses hiring practices in Chile in relation to the scarcity of women in leadership positions in Chile. It problematizes the discourse about hiring and selection practices in contrast with the current employment law.
Rosario Undurraga, Emmanuelle Barozet
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source