Results 51 to 60 of about 449,004 (237)

Lung morphology predicts response to recruitment maneuver in patients with acute respiratory distress syndrome

open access: yes, 2010
International audienceObjectives: The impact of recruitment maneuvers on gas exchange, hemodynamics, alveolar recruitment, and hyperinflation is highly variable among patients with acute respiratory distress syndrome.
Constantin, Jean-Michel   +10 more
core   +1 more source

Changes in stroke volume during an alveolar recruitment maneuvers through a stepwise increase in positive end expiratory pressure and transient continuous positive airway pressure in anesthetized patients. A prospective observational pilot study

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2019
Background and Aims: Recruitment maneuvers may be used during anesthesia as part of perioperative protective ventilation strategy. However, the hemodynamic effect of recruitment maneuvers remain poorly documented in this setting.
Jean Luc Hanouz   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Modeling Lung Derecruitment in VILI Due to Fluid-Occlusion: The Role of Emergent Behavior

open access: yesFrontiers in Physiology, 2020
Ventilator-induced lung injury (VILI) is driven by the processes of volutrauma and atelectrauma, which can act synergistically to compromise the blood-gas barrier.
Vitor Mori   +4 more
doaj   +1 more source

The effect of intraoperative lung protective ventilation vs conventional ventilation, on postoperative pulmonary complications after cardiopulmonary bypass [PDF]

open access: yesJournal of Cardiovascular and Thoracic Research, 2017
Introduction: This study aimed to evaluate the effects of high positive-end expiratory pressure (PEEP) and low tidal volume (TV) and recruitment maneuver, on postoperative pulmonary complications (PPCs) after coronary artery bypass grafting (CABG ...
Mohammad Mahdi Zamani   +10 more
doaj   +1 more source

Evaluation of the efficiency of highly realistic simulation during the selection of ALV parameters in ARDS

open access: yesВестник анестезиологии и реаниматологии, 2023
The objective wasto evaluate the efficiency of the highly realistic simulator “Test Chest” in training residents in the specialty “Anesthesiology and Resus-citation” in the alveolar recruitment maneuver and the de-escalation option for setting positive ...
K. A. Tsygankov   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Lung recruitment in ARDS patients

open access: yesActa Medica Lituanica, 2012
Lung recruitment is used to improve oxygenation and decrease the risk of ventilator induced lung injuries. Assessing the potential of recruitability is a pre-requisite for a rational recruitment strategy and setting of PEEP.
Jean-Michel Arnal, Aude Garnero
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Yacovino Maneuver or the Deep Head Hanging Maneuver for AC-BPPV (Video)

open access: yes, 2023
The Yacovino maneuver is used to treat anterior canal benign paroxysmal positional vertigo (AC-BPPV) and does not require the clinician to distinguish which side is involved. Additionally, when the patient completes cervical flexion, the motion may cause
Allison Nogi, DPT
core  

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