Results 61 to 70 of about 449,004 (237)

Lung recruitment mechanics: coalescing tissue strains with organ expansion

Respiratory Research
Background Recruitment maneuvers are used to prevent atelectasis, or partial lung collapse, and to help prevent ventilator induced lung injury. Recruitment techniques remain a topic of debate due to the possibility for damage as they necessitate higher ...
M. Shankel, T. M. Nelson, K. A. M. Quiros, J. Bebawy, C. A. Mariano, T. Biddle, D. D. Lo, M. Eskandari   +7 more
doaj   +1 more source

Volume-controlled ventilation versus pressure-controlled ventilation and recruitment maneuvers in video-assisted thoracoscopic surgery

Gülhane Tıp Dergisi, 2023
Aims:Various ventilation strategies can be applied to prevent lung injury during one-lung ventilation (OLV). We compared intraoperative ventilation strategies in terms of haemodynamic and respiratory parameters in video-assisted thoracoscopic surgery ...
Esra Sarı, Hilal Sazak, Mehtap Tunç, Fatma Ulus, Ali Alagöz   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Effect of PEEP titration on the incidence of elevated driving pressure in laparoscopic bariatric surgery: a randomized superiority trial

BMC Anesthesiology
Background Suboptimal positive end-expiratory pressure (PEEP) settings may lead to cyclic lung overstress, especially in obese patients undergoing general anesthesia. We hypothesized that recruitment maneuver (RM) followed by driving pressure–guided PEEP
Saullo Queiroz Silveira, Sérgio M. Pereira, Leopoldo Muniz da Silva, Rafael Souza Fava Nersessian, Helidea de Oliveira Lima, Desiree Stieven Machado, João Pedro Borghi Moreira, Fernando Nardy Bellicieri, Glenio B. Mizubuti, Joaquim Edson Vieira   +9 more
doaj   +1 more source

Physiologic responses to a staircase lung volume optimization maneuver in pediatric high-frequency oscillatory ventilation

Annals of Intensive Care, 2020
Background Titration of the continuous distending pressure during a staircase incremental–decremental pressure lung volume optimization maneuver in children on high-frequency oscillatory ventilation is traditionally driven by oxygenation and hemodynamic ...
Pauline de Jager, Johannes G. M. Burgerhof, Alette A. Koopman, Dick G. Markhorst, Martin C. J. Kneyber   +4 more
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Lung recruitment with HFOV versus VTV/AC in preterm infants with RDS

BMC Pediatrics
Objectives To compare the effect of lung recruitment using high frequency ventilation versus volume targeted ventilation on duration of intubation as well as its effect on lung inflammation in preterm infants with respiratory distress syndrome.
Marwa Eldegwi, Ali Shaltout, Osama Elagamy, Dina Salama, Mohammed Elshaer, Basma Shouman   +5 more
doaj   +1 more source

Physiologic effects of alveolar recruitment and inspiratory pauses during moderately-high-frequency ventilation delivered by a conventional ventilator in a severe lung injury model. [PDF]

PLoS ONE, 2017
To investigate whether performing alveolar recruitment or adding inspiratory pauses could promote physiologic benefits (VT) during moderately-high-frequency positive pressure ventilation (MHFPPV) delivered by a conventional ventilator in a porcine model ...
Ricardo Luiz Cordioli, Eduardo Leite Vieira Costa, Luciano Cesar Pontes Azevedo, Susimeire Gomes, Marcelo Britto Passos Amato, Marcelo Park   +5 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Effect of Pulmonary Recruitment Maneuver on Postlaparoscopic Shoulder Pain, Postoperative Pain and Outcomes in Gynecologic Laparoscopic Surgeries [PDF]

Objective: Post-laparoscopic shoulder pain (PLSP) is a significant occurrence after laparoscopic surgery. This study investigated the effects of pulmonary recruitment maneuvers (PRM) on PLSP, postoperative pain, and patient outcomes in patients ...
Naime Yalçın, Hale Çetin Arslan, Kadir Arslan, Ayça Sultan Şahin   +3 more
core   +1 more source