Results 101 to 110 of about 113,224 (248)

Corrigendum: Phenotypic and genetic parameters of circadian rhythms from core body temperature profiles and their relationships with beef steers’ production efficiency profiles during successive winter feeding periods

Frontiers in Genetics, 2023
Obioha Durunna, Obioha Durunna, Jeffery A. Carroll, Jeff W. Dailey, Daalkhaijav Damiran, Kathy A. Larson, Edouard Timsit, Rex Parsons, Ghader Manafiazar, Herbert A. Lardner   +9 more
doaj   +1 more source

Rectal HSV-2 Infection May Increase Rectal SIV Acquisition Even in the Context of SIVΔnef Vaccination. [PDF]

, 2016
Prevalent HSV-2 infection increases the risk of HIV acquisition both in men and women even in asymptomatic subjects. Understanding the impact of HSV-2 on the mucosal microenvironment may help to identify determinants of susceptibility to HIV. Vaginal HSV-
Rosaline Truong, Natalia Guerra-Pérez, Truong, Rosaline, Grasperge, Brooke, Elena Martinelli (206264), Meropi Aravantinou, Goode, Diana, Agegnehu Gettie, Aravantinou, Meropi, Melissa Robbiani, Nina Derby, Goode, Diana J., Elena Martinelli, Diana Goode, Gettie, Agegnehu, Agegnehu Gettie (215440), Brooke Grasperge (528109), Meropi Aravantinou (51206), Martinelli, Elena, Filippo Veglia (1888180), Diana Goode (564814), Nina Derby (528107), James Blanchard, James Blanchard (215437), Veglia, Filippo, Filippo Veglia, Guerra-Perez, Natalia, Rosaline Truong (106404), Guerra Pérez, Natalia, Melissa Robbiani (51208), Robbiani, Melissa, Brooke Grasperge, Blanchard, James, Natalia Guerra-Pérez (1888177), Derby, Nina   +34 more
core   +1 more source

Tissue‐Agnostic Cellular Morphometric Biomarkers for Risk‐Adapted Management Across Gastrointestinal Precancerous Lesions and Cancers

Advanced Science, EarlyView.
An interpretable, unsupervised artificial intelligence framework identifies a 13‐cellular morphometric biomarker (CMB) signature from routine H&E whole‐slide images. Validated across 2,602 patients, the fixed signature generalizes across colorectal, gastric, and esophageal tissues without retraining, stratifies prognosis and precancerous lesion risk ...
Pin Wang, Chengfei Jiang, April W. Mao, Qi Sun, Yijun Lu, Jingjing Wei, Jamie L. Inman, Susan E. Celniker, Antoine M. Snijders, David W. Threadgill, Allan Balmain, Bo Hang, Hang Chang, Lei Wang, Jian‐Hua Mao   +14 more
wiley   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Uhrf1‐Mediated PKM2 Degradation via Ubiquitination Alleviates Inflammation and Pyroptosis in Inflammatory Bowel Disease

Advanced Science, EarlyView.
Uhrf1‐mediated PKM2 ubiquitination and degradation repressed the nuclear translocation of PKM2, and EPT served as a molecular glue capable of targeting the Uhrf1–PKM2 complex to alleviate the IBD course, suggesting that the Uhrf1–PKM2 axis was a previously unrecognized strategy for treating IBD.
Juan Zhang, Xin‐Rong Xu, Hui‐Lin Zhang, Qi‐Meng Zhu, Xin‐Yuan Li, Xi‐Peng Shang, Jing‐Hui Du, Christophe Morisseau, Feng Qiu, Cheng‐Peng Sun   +9 more
wiley   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

Short-term and long-term outcomes after robotic radical surgery for rectal gastrointestinal stromal tumor

BMC Surgery
Background The optimal approach for ensuring both complete resection and preservation of anal function in rectal gastrointestinal stromal tumor (GIST) remains unknown.
Chikara Maeda, Yusuke Yamaoka, Akio Shiomi, Hiroyasu Kagawa, Hitoshi Hino, Shoichi Manabe, Chen Kai, Kenji Nanishi   +7 more
doaj   +1 more source

Rectal and axillary admission temperature in preterm infants less than 32 weeks' gestation, a prospective study

Frontiers in Pediatrics
ObjectivesThe purpose of this research was to evaluate the differences between rectal and axillary temperature measurements in preterm infants who were born less than 32 weeks’ gestation using digital thermometers upon their admission to the Neonatal ...
Shaimaa Halabi, Shaimaa Halabi, Rana Almuqati, Amenah Al Essa, Manal Althubaiti, Musab Alshareef, Radha Mahlangu, Abdulaziz Homedi, Faisal Alsehli, Faisal Alsehli, Saif Alsaif, Saif Alsaif, Saif Alsaif, Kamal Ali, Kamal Ali, Kamal Ali   +15 more
doaj   +1 more source

Proactive rectal warming during total-gland prostate cryoablation

, 2017
Purpose: Proactive rectal warming (PRW), as a modification of prostate cryoablation, was assessed in terms of rectal complications and therapeutic outcomes. ;Materials and methods: A cohort of 166 patients cumulatively treated between September, 2009 and
Chen, Chung-Hsin;Pu, Yeong-Shiau, 蒲永孝;陳忠信   +1 more
core   +1 more source

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

Advanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia, Jia‐Xin Liu, Rui‐Ping Wang, Xue‐Qin Wu, Yao Che, Mu‐Chen Wu, Hong‐Wei Shang, Xin Lu, Tao Lu, Lu‐Lu Wang, Chun‐Yan Jiang, Dong‐Liang Fang, Chun Yang, Yan Gao   +13 more
wiley   +1 more source