Results 131 to 140 of about 4,845,209 (387)

Multifractal characteristics of external anal sphincter based on sEMG signals

, 2017
This work presents the application of Multifractal Detrended Fluctuation Analysis for the surface electromyography signals obtained from the patients suffering from rectal cancer.
Machura, Lukasz, Nowakowski, Michal, Trybek, Paulina   +2 more
core   +1 more source

High survivin expression as a risk factor in patients with anal carcinoma treated with concurrent chemoradiotherapy [PDF]

, 2012
Purpose: To investigate the prognostic value of survivin expression in pretreatment specimens from patients with anal cancer treated with concurrent 5-FU and mitomycin C-based chemoradiation (CRT).
Distel, Luitpold Valentin Rudolf, Falk, Stefan, Fraunholz, Ingeborg, Kohler, Daniela, Rave-Fränk, Margret, Rödel, Claus, Rödel, Franz   +6 more
core   +2 more sources

The Role of CAF‐derived Vitronectin in Promoting Colorectal Cancer Progression and Immunosuppression

Advanced Science, EarlyView.
Cancer‐associated fibroblast (CAF)‐derived VTN upregulates SLC6A8 expression in colorectal cancer (CRC) cells and macrophages through enhanced FAK phosphorylation. This modulation significantly increases the cellular uptake of creatine and ATP, promoting cancer progression and macrophage polarization.
Jiahua Yu, Mengxi Xiu, Shijun Yu, Zhiqin Chen, Yandong Li, Yong Gao   +5 more
wiley   +1 more source

Diagnosis, treatment and full-process surveillance of early rectal cancer [PDF]

Waike lilun yu shijian
Early rectal cancer is defined as any size of rectal epithelial tumor with infiltration depth limited to the mucosa and submucosa, regardless of with or without lymph node metastasis.
LAN Ping, CHEN Yongle, HE Xiaosheng
doaj   +1 more source

Magnetic Resonance Guided Radiotherapy for Rectal Cancer: Expanding Opportunities for Non-Operative Management

Cancer Control, 2020
Colorectal cancer is the third most common cancer in men and the second most common in women worldwide, and the incidence is increasing among younger patients. 30% of these malignancies arise in the rectum.
Leila T. Tchelebi MD, Paul B. Romesser MD, Sebastian Feuerlein MD, Sarah Hoffe MD, Kujtim Latifi PhD, Seth Felder MD, Michael D. Chuong MD   +6 more
doaj   +1 more source

Genomic and transcriptomic determinants of response to neoadjuvant therapy in rectal cancer

Nature Network Boston, 2022
Walid K. Chatila, Jin K. Kim, H. Walch, Michael R. Marco, Ching-Tung Chen, Fan Wu, D. Omer, D. Khalil, K. Ganesh, X. Qu, A. Luthra, Seo-Hyun Choi, Yu-jui Ho, Ritika Kundra, Katharine I Groves, O. Chow, A. Cercek, M. Weiser, M. Widmar, I. Wei, E. Pappou, G. Nash, P. Paty, Q. Shi, E. Vakiani, S. Duygu Selcuklu, M. Donoghue, D. Solit, M. Berger, J. Shia, Raphael A. Pelossof, P. Romesser, R. Yaeger, J. Smith, N. Schultz, F. Sánchez-Vega, J. García-Aguilar   +36 more
semanticscholar   +1 more source

Association Between Adjuvant Chemotherapy and Overall Survival in Patients With Rectal Cancer and Pathological Complete Response After Neoadjuvant Chemotherapy and Resection

JAMA Oncology, 2018
Importance Although American guidelines recommend use of adjuvant chemotherapy in patients with locally advanced rectal cancer, individuals who achieve a pathological complete response (pCR) following neoadjuvant chemoradiotherapy are less likely to ...
F. Dossa, S. Acuna, A. Rickles, M. Berho, S. Wexner, F. Quereshy, N. Baxter, S. Chadi   +7 more
semanticscholar   +1 more source

Akkermansia muciniphila‐Derived N‐Acetylspermidine Modulates the Localization of Intestinal α1,2‐Fucosylated Proteins to Maintain Gut Homeostasis

Advanced Science, EarlyView.
This study demonstrates that Akkermansia muciniphila alleviates colitis by enhancing intestinal α1,2‐fucosylation through its metabolite N‐acetylspermidine. Mechanistically, N‐acetylspermidine‐induced PIM1 inhibition promotes HDAC2‐mediated reduction of chromatin accessibility at TP73, thereby upregulating C1GALT1C1 to boost α1,2‐fucosylation.
Ye Yao, Zhangming Pei, Yuanyuan Dai, Yinghan Chen, Zepeng Chang, Hongchao Wang, Jianxin Zhao, Hao Zhang, Qixiao Zhai, Wenwei Lu, Wei Chen   +10 more
wiley   +1 more source

Comparison of the prognostic value of tumour and patient related factors in patients undergoing potentially curative surgery for colon cancer [PDF]

, 2010
<b>Aim</b>: To comprehensively compare the prognostic value of tumour and patient-related factors in patients undergoing curative surgery for colon cancer.
Benson, Brown, Compton, Cooper, Crozier, Dukes, Forrest, Gabay, Gasser, Halazun, Hauser, Ishizuka, Kacevska, Kandemir, Kim, Kobayashi, Lee, Leitch, Lindmark, Maltoni, McMillan, McMillan, Mehrkhani, Michael, Moertel, Monreal, Morris, Petrelli, Ramsey, Roxburgh, Sasaki, Sharma, Smith, Taylor, Thynne, Vakkila, Vibert, Viganó, Walsh, Wanebo, Wang, Wolpin   +41 more
core   +1 more source

Effects of metformin and phenformin on apoptosis and epithelial‐mesenchymal transition in chemoresistant rectal cancer

Cancer Science, 2019
Recurrence and chemoresistance in colorectal cancer remain important issues for patients treated with conventional therapeutics. Metformin and phenformin, previously used in the treatment of diabetes, have been shown to have anticancer effects in various
Ji-Hye Park, Young-Heon Kim, E. H. Park, Sun-Joo Lee, Hyewon Kim, A. Kim, Seung Bum Lee, Sehwan Shim, H. Jang, J. Myung, Sunhoo Park, Su-Jae Lee, M. J. Kim   +12 more
semanticscholar   +1 more source