Results 121 to 130 of about 5,235,363 (361)

Patterns of metastasis in colon and rectal cancer

Scientific Reports, 2016
Investigating epidemiology of metastatic colon and rectal cancer is challenging, because cancer registries seldom record metastatic sites. We used a population based approach to assess metastatic spread in colon and rectal cancers.
M. Riihimäki, A. Hemminki, J. Sundquist, K. Hemminki   +3 more
semanticscholar   +1 more source

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

Advanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu, Chao Xu, Jun Jiang, Limin He, Yike Zhou, Zhengxuan Li, Yu Li, Keying Zhang, Fa Yang, Tong Lu, Hongtao Song, Hai Zhu, Zhihao Hu, Xiaolong Zhao, Kai Gan, Hongji Li, Bo Yang, Rui Zhang, Weihong Wen, Donghui Han, Weijun Qin   +20 more
wiley   +1 more source

Tissue-associated bacterial alterations in rectal carcinoma patients revealed by 16S rRNA community profiling

Frontiers in Cellular and Infection Microbiology, 2016
Sporadic and inflammatory forms of colorectal cancer (CRC) account for more than 80% of cases. Recent publications have shown mechanistic evidence for the involvement of gut bacteria in the development of both CRC-forms.
Andrew Maltez Thomas, Andrew Maltez Thomas, Andrew Maltez Thomas, Eliane Camargo de Jesus, Eliane Camargo de Jesus, Ademar Lopes, Samuel Aguiar Junior, Maria Dirlei Begnami, Rafael Malagoli Rocha, Paola Avelar Carpinetti, Anamaria Aranha Camargo, Christian Hoffmann, Helano Carioca Freitas, Helano Carioca Freitas, Israel Tojal da Silva, Diana Noronha Nunes, Joao Carlos Setubal, Joao Carlos Setubal, Emmanuel Dias-Neto, Emmanuel Dias-Neto   +19 more
doaj   +1 more source

Volumetric modulated arc therapy with simultaneous integrated boost for locally advanced rectal cancer

, 2012
To report the feasibility of volumetric modulated arc therapy (VMAT) for neoadjuvant radiotherapy in locally advanced rectal cancer in a dose-escalation protocol and simultaneous integrated boost (SIB) approach.
Deodato F, V. Picardi, M. Massaccesi, Digesù C, A. Piermattei, Piermattei, Angelo, Cilla, Savino, Morganti, Alessio Giuseppe, Picardi, Vincenzo, Caravatta, Luciana, Caravatta L, Macchia, Gabriella, Digesu', Cinzia, Picardi V, Massaccesi, Mariangela, Macchia G, Cilla S, D. Sabatino, Sabatino D, Deodato, Francesco, G. Macchia, S. Cilla, A.G. Morganti, De Spirito M, M. De Spirito, Sabatino, Domenico, De Spirito, Marco, C. Digesù, Massaccesi M, Piermattei A, L. Caravatta, F. Deodato   +31 more
core   +1 more source

Adjuvant Radiation for Rectal Cancer: Do We Measure Up to the Standard of Care? An Epidemiologic Analysis of Trends Over 25 Years in the United States [PDF]

, 2005
In the United States, adjuvant radiation therapy is currently recommended for most patients with rectal cancer. We conducted this population-based study to evaluate the rate of radiation therapy and the factors affecting its delivery.Peer Reviewedhttp ...
Baxter, N. N., Rothenberger, D. A., Bullard, Kai McKeever, Morris, A. M.   +3 more
core   +1 more source

Advances in Cancer Immunotherapy for Solid Tumors

Advanced Science, EarlyView.
Cancer immunotherapy for solid tumors is rapidly evolving beyond classical checkpoint blockade toward more precise strategies. Emerging checkpoint targets, bispecific antibodies, antibody–drug conjugate combinations, personalized vaccines, cellular therapies, and engineered cytokines are expanding therapeutic possibilities, while biomarker‐guided ...
Shira Gabizon‐Peretz, Harriet M. Kluger   +1 more
wiley   +1 more source

Circulating Amino Acid Network Remodeling Reveals Systemic Metabolic Reprogramming Predictive of Colorectal Cancer Recurrence and Metastasis

Advanced Science, EarlyView.
Blood‐based amino acid patterns measured by 19F NMR reveal hidden metabolic changes in colorectal cancer. By analyzing how these amino acids interact as a network, machine learning models identify patients at higher risk of recurrence and metastasis.
Ji‐Yeon Lee, Jumi Kim, Taehan Yoon, So Hyun Kwon, Su Chan Park, Dohyun Chun, Dohyeong Kim, Eun Jung Park, Hyunwoo Kim, Ji Min Lee   +9 more
wiley   +1 more source

TCF7 transcriptional activation of MACC1 regulates aerobic glycolysis and promotes oxaliplatin resistance in rectal cancer [PDF]

Zhongguo aizheng zazhi
Background and purpose: Rectal cancer occurs on the inner wall of the rectum, and metastasis-associated in colon cancer 1 (MACC1) can promote drug resistance in colon cancer cells.
YAN Yan, ZHOU Liqing, XIA Jianhong, MA Tingting
doaj   +3 more sources

Rectal Cancer [PDF]

Clinics in Colon and Rectal Surgery, 2015
James W, Fleshman, Warren E, Lichliter
openaire   +2 more sources

Minilaparotomy Approach Employing a K?stner Incision for Rectal Cancer Resection: Report of Three Cases [PDF]

, 2008
A minilaparotomy approach (? 7 cm) for colorectal cancer resection is feasible and safe. Such minilaparotomy generally employs a small vertical incision.
Murakami, Goushi, Kondou, Masamichi, Nonaka, Yosikazu, Ryu, Chusei, Nakagoe, Tohru, Nakamura, Shirou, Matsuo, Toshikazu   +6 more
core