Results 181 to 190 of about 5,235,363 (361)
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The Homologous Recombination Factor With OB‐Fold (HROB) plays a role in homologous recombination and DNA replication, where it enhances the MCM8‐MCM9 helicase complex activity. Recent findings link biallelic germline HROB variants to primary gonadal insufficiency (hypergonadotropic hypogonadism), a phenotype also associated with MCM8/MCM9 ...
Noah C. Helderman +15 more
wiley +1 more source
Solitary rectal ulcer syndrome: MRI findings and differentiation from rectal cancer
Insights into ImagingBackground Systematic MRI findings of solitary rectal ulcer syndrome (SRUS) are lacking. We aimed to evaluate the MRI findings of SRUS and to identify the MRI features that differentiate SRUS from rectal cancer.
Peiyi Xie +9 more
doaj +1 more source
Animal Research and One Health, EarlyView.Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang +6 more
wiley +1 more source
Immune microenvironment in elderly patients with rectal cancer
reservedBackground: Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide, with its incidence rates increasing with age. Age is a significant prognostic factor in CRC, and different age groups exhibit distinct characteristics ...
MARINELLI, LAURA
core
British Journal of Clinical Pharmacology, EarlyView.Aims Predetermined treatment duration limits (PTDLs) are often used by Taiwan's National Health Insurance Administration to contain healthcare costs, but they may compromise patient outcomes. Therefore, we studied Taiwan's 2017 extension of the bevacizumab PTDL from 24 to 36 weeks in metastatic colorectal cancer (mCRC) to evaluate whether prolonged ...
Wei‐Ming Huang +6 more
wiley +1 more source
NOVA SCOTIA RECTAL CANCER PROJECT: A POPULATION BASED ASSESSMENT OF RECTAL CANCER CARE AND OUTCOMES
, 2011 Purpose: To describe patient & tumor characteristics among rectal cancer patients in Nova Scotia, to determine factors associated with permanent colostomy and oncologic outcomes and to determine the relationship between surgeon knowledge and oncologic ...
Richardson, Devon Paula
core
British Journal of Clinical Pharmacology, EarlyView.Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad +4 more
wiley +1 more source
Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Annals of Oncology, 2017 R. Glynne-Jones +6 more
semanticscholar +1 more source
Chronic Diseases and Translational Medicine, EarlyView.Features the major cell type compositions among colon and liver metastasis. (A) The study design for single‐cell data analysis. (B) The annotated major cell types. Each type was labeled with a special color. (C) Dot plot of canonical marker genes for major cell types. (D) Bar plot of the percentage for each cell type in individuals. (E) Bar plot of the
Zhixun Zhao +10 more
wiley +1 more source