Advancements in Rectal Drug Delivery Systems: Clinical Trials, and Patents Perspective
The rectal route is an effective route for the local and systemic delivery of active pharmaceutical ingredients. The environment of the rectum is relatively constant with low enzymatic activity and is favorable for drugs having poor oral absorption ...
Ritu Rathi +6 more
doaj +3 more sources
MRI in local staging of rectal cancer: an update [PDF]
Preoperative imaging for staging of rectal cancer has become an important aspect of current approach to rectal cancer management, because it helps to select suitable patients for neoadjuvant chemoradiotherapy and determine the appropriate surgical ...
Ümit Tapan +2 more
doaj +2 more sources
Unraveling the Rectal Virome: Microbial Crosstalk, Immune Modulation, and Clinical Outcomes in People with and Vulnerable to HIV [PDF]
The rectal mucosa houses a large number of viruses with important roles in shaping the local microbial communities and modulating immune responses, which could influence host susceptibility to infection and other diseases.
Ruth S. Bako, Colleen F. Kelley
doaj +2 more sources
Comparative Analysis of Fistulotomy and Fistulectomy in Managing Low Anal Fistulas [PDF]
Introduction- Infected anal crypts are the most prevalent cause of an anal fistula, a pathological relationship that exists between the anal canal and perianal skin. The present study aimed to compare fistulotomy and fistulectomy in the management of low
Mohammad Shahbaz +2 more
doaj +1 more source
Extraperitoneal Spread of Anorectal Abscess: A Case Report and Literature Review [PDF]
Supralevator abscess is a rare form of anorectal disease responsible for very rare but morbid manifestations, one of which is superior spread through fascial planes.
Papadopoulos S. Konstantinos +3 more
doaj +1 more source
Still a Case of “No Pain, No Gain”? An Updated and Critical Review of the Pathogenesis, Diagnosis, and Management Options for Hemorrhoids in 2020 [PDF]
The treatment of haemorrhoids remains challenging: multiple treatment options supported by heterogeneous evidence are available, but patients rightly demand a tailored approach.
Kheng-Seong Ng +2 more
doaj +1 more source
Introduction Colonoscopy enables detailed endoscopic evaluation of the interior of the colon. Changes observed via colonoscopy may be subtle or pronounced and can sometimes mimic those of other diseases, such as deep intestinal endometriosis.
Vinicius Pfuetzenreiter +3 more
doaj +1 more source
Rectal and Colonic Ulceration in Behçet's Disease [PDF]
Abstract Two patients with Behçet's disease and involvement of the gastro-intestinal tract are described. One patient presented with rectal bleeding and perianal pain, and later developed peritonitis due to perforation of the sigmoid colon.
D W, Empey, J E, Hale
openaire +4 more sources
Rectal syphilis - a case report [PDF]
Introduction. Syphilis rarely affects anorectal region. The symptoms are nonspecific and are commonly disregarded in our country. Therefore, they pose a difficulty both for a diagnosis and for a treatment.We presented a patient with the clinical ...
Damjanov Dimitrije +8 more
doaj +1 more source
Clinical and epidemiological study of rectal cancer [PDF]
Background. In this article, we present a study that tries to characterize the patient with rectal cancer who addresses the Brașov County Emergency Clinical Hospital (SCJUBv). Aim.
Andrei Iulian Toader +4 more
doaj +1 more source

