Results 101 to 110 of about 33,126 (300)

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

T1‐weighted fMRI in mouse visual cortex using an iron oxide nanoparticle contrast agent and UTE imaging at 9.4 T

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose This study aims to investigate the feasibility of using T1‐weighted fMRI with an iron oxide nanoparticle contrast agent and UTE imaging at 9.4 T to measure functional hyperemia in the mouse visual cortex. The goal is to capture positive signal changes in both the parenchyma and pial surface, and to test whether surface vessels respond ...
Naman Jain, Saskia Bollmann, Kai‐Hsiang Chuang, Jonathan R. Polimeni, Markus Barth   +4 more
wiley   +1 more source

Assessment of Double Outlet Left Ventricle in Pediatrics Using Transthoracic Echocardiography and Computed Tomographic Angiography

Pediatric Discovery, EarlyView.
The clinical manifestation of DOLV was atypical. TTE has a relatively high diagnostic accuracy for DOLV in pediatric, which is very valuable for its early detection. ABSTRACT Double outlet left ventricle (DOLV) is a rare congenital cardiac anomaly in which both great arteries originate entirely or predominantly from the morphologic left ventricle.
Xu Zhu, Guangyi Zhong, Xiaojuan Ji, Xue Xiang, Min Zheng, Huina Yan, Rui Li   +6 more
wiley   +1 more source

Gallstone ileus treated with non-surgical conservative methods: a case report [PDF]

, 2015
INTRODUCTION: The preoperative diagnosis of gallstone ileus is challenging due to the variability of its presentation, often resulting in late diagnosis.
Fusetti, N, Maimone, A, Pezzoli, A, Pizzo, E   +3 more
core   +1 more source

Disease Monitoring in Inflammatory Bowel Disease Daily Clinical Practice and Impact on Treatment Decision Making: Real World Evidence From the Inflammatory Bowel Disease‐PODCAST Study

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background Crohn's disease (CD) and ulcerative colitis (UC) are progressive inflammatory bowel diseases that often result in bowel damage, imposing a significant burden on patients with insufficient disease control due to the limited efficacy of current treatments or complex disease management.
Axel Dignass, Fernando Magro, Ferdinando D’Amico, Giorgos Bamias, Flavio Andrea Caprioli, Denis Franchimont, Ailsa Hart, Robert Koch, Ioannis Koutroubakis, Jesse Siffledeen, Murat Toruner, Claudia Leitner, Tobias Heatta‐Speicher, Naiara Michelena, Valentina Tornatore, Lorenzo Gemignani, Jennifer Lapthorn, Laura Kauffman, Fernando Gomollón, on behalf of theIBD‐PODCAST Investigators   +19 more
wiley   +1 more source

Congenital H-type recto-vaginal fistula with normal anus: a case report

Journal of Pediatric Surgery Case Reports
Introduction: Congenital H-type fistula is a rare anomaly characterized by a recto-urogenital connection, with the external anal opening potentially positioned normally or ectopically.
Samuel Kefiyalew Kelbessa, Berhanu Nigusse Bikila, Amanuel Mesfin Oljira   +2 more
doaj   +1 more source

Practice parameters for the treatment of colonic diverticular disease: Italian Society of Colon and Rectal Surgery (SICCR) guidelines [PDF]

, 2015
The mission of the Italian Society of Colorectal Surgery (SICCR) is to optimize patient care. Providing evidence-based practice guidelines is therefore of key importance.
Annibale, Bruno, Bellini, Davide, Binda, G. A, Cuomo, R, Gervaz, P, Laghi, Andrea, Nascimbeni, R, Serventi, A   +7 more
core   +2 more sources

A persistent hymen resulting in an open cervix but closed pyometra and pyocolpos in a mixed‐breed female domestic dog

Veterinary Record Case Reports, EarlyView.
Abstract A rescued mixed‐breed (Africanis type), entire, female dog, approximately 2 years old, with an unknown history, presented with a prominent perineal swelling between the anus and vulva. Ultrasound identified it as a fluid‐filled structure, and an aspirate revealed an exudate consisting of degenerate neutrophils, bacterial cocci and rods.
Taylor June Kruger, Adriaan Kitshoff, Johan P. Schoeman, Sara Nicolene Hoepner, Josef Hanekom   +4 more
wiley   +1 more source

Endoscopic closure of a rectal fistula using a cardiac septal defect occluder: the final redemption. [PDF]

Endoscopy, 2023
Medas R, Rodrigues-Pinto E, Silva JC, Pereira P, Macedo G.   +4 more
europepmc   +1 more source

Ileorectal fistula due to a rectal cancer—A case report

International Journal of Surgery Case Reports, 2011
A 51-year-old man was seen at our hospital because of diarrhea. Barium enema and colonoscopy revealed a cancer in the lower rectum and fistula formation from the site to ileum. Resection of the rectal cancer and ileorectal fistula was performed. Histologically, the resected lesion was mucinous adenocarcinoma with contiguous invasion from the rectum to ...
Minoru Takahashi, Takahiro Fukuda
openaire   +3 more sources