Results 91 to 100 of about 553,594 (272)

Curative endoscopic resection for a recurrent rectal neoplasm with massive submucosal fibrosis after a transanal endoscopic microsurgery‐associated leak [PDF]

, 2021
Naoya TADA, Hideki Kobara, Tsutomu Masaki   +2 more
openalex   +1 more source

FXYD3 Promotes Tumor Progression by Binding With IRF7 to Regulate JAK2/STAT5 Signaling in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
FXYD3 binds IRF7 via its 60–87aa domain, triggering a cGAS/STING‐mediated positive feedback loop amplified by type I interferon. This sustains JAK2/STAT5 activation, accelerating ICC progression. Targeting FXYD3 with siFXYD3@PEP suppresses tumors and enhances chemotherapy sensitivity. Abstract Intrahepatic cholangiocarcinoma (ICC) has a poor prognosis,
Yan Zhou, Xiaofeng Shen, Shuo Zhang, XiaoHong Pu, Zipeng Xu, Xiang Zhao, Wei Feng, Yuan Liang, Xingtao He, Aihua Yang, Yudong Qiu, Yihang Yuan, Chaobo Chen, Jun Chen   +13 more
wiley   +1 more source

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

BJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)   +18 more
wiley   +1 more source

Association of Radiotherapy for Rectal Cancer and Second Gynecological Malignant Neoplasms [PDF]

, 2021
Xu Guan, Ran Wei, Runkun Yang, Zhaohui Lu, Enrui Liu, Zhixun Zhao, Haipeng Chen, Ming Yang, Zheng Liu, Zheng Jiang, Xishan Wang   +10 more
openalex   +1 more source

ARL5B Drives Esophageal Squamous Cell Carcinoma Progression via ROCK1–SREBP1‐Mediated Lipid Metabolic Reprogramming

Advanced Science, EarlyView.
Esophageal squamous cell carcinoma urgently requires new therapeutic strategies. Adenosine diphosphate‐ribosylation factor‐like protein 5B (ARL5B) is identified as a novel oncogene that remodels fatty acid metabolism through the ras homologous‐associated coiled‐coil containing protein kinase 1 (ROCK1)–sterol regulatory element‐binding protein 1 (SREBP1)
Xinyue Ma, Yanfei Sun, Hongyuan Mao, Chenhan Huang, Zerun Li, Tianzi Wang, Dizhi Jiang, Xinyu Zhang, Zhenyu Yuan, Zhihui Zhang, Bo Cheng, Ruiqing Wang, Yufeng Cheng   +12 more
wiley   +1 more source

Exceptional cause of bowel obstruction: rectal endometriosis mimicking carcinoma of Rectum - a case report

The Pan African Medical Journal, 2011
Endometriosis with intestinal serosal involvement is not uncommon in women of childbearing age. However, endometriosis presenting as colon obstruction is rare and occurs in less than 1% of cases.
Selim Sassi, Mahdi Bouassida, Hassen Touinsi, Mohamed Mongi Mighri, Sonia Baccari, Fathi Chebbi, Khaled Bouzeidi, Sadok Sassi   +7 more
doaj   +1 more source

Corrigendum to “Surgical outcomes of robotic transanal minimally invasive surgery for selected rectal neoplasms: A single-hospital experience” [Asian J Surg. 43 (1) (2020 Jan) 290–296]

, 2021
Yan‐Jiun Huang, Yu‐Min Huang, Wei–Lin Wang, Yiu-Shun Tong, Wayne Hsu, Po‐Li Wei   +5 more
openalex   +1 more source

T Cell Exhaustion and Dendritic Cell‐Mediated Tertiary Lymphoid Structures (TLSs) Modulation Affect Response to Neoadjuvant Chemoradiotherapy in Microsatellite Stable Rectal Cancer

Advanced Science, EarlyView.
Using multi‐omics analysis, this study demonstrates that immune characteristics of the tumor microenvironment, rather than mutational profiles, are more strongly correlated with treatment response. Specifically, early exhausted T cells and tertiary lymphoid structures regulation by LAMP3⁺ dendritic cells emerge as key predictors of favorable outcomes ...
Miao Wang, Jiejun Shi, Kai Xu, Leyi Yu, Xiaomao Yin, Jiexuan Wang, Lin Zhu, Xin Yang, Jingjing Qian, Wenqiang Wang, Liangchen Zhu, Xuan Dai, Zekun Zhao, Jinran Wu, Dongsheng Li, Zhiqian Hu, Qi Huang, Xinxing Li   +17 more
wiley   +1 more source

Incidence of synchronous appendiceal neoplasm in patients with colorectal cancer and its clinical significance

World Journal of Surgical Oncology, 2009
Background The aims of this study were to evaluate the incidence of synchronous appendiceal neoplasm in patients with colorectal cancer, and to determine its clinical significance.
Lohsiriwat Darin, Vongjirad Akkrarash, Lohsiriwat Varut   +2 more
doaj   +1 more source

Safety and Efficacy of Pelvic Reinforcement Procedure for Preventing Postoperative Perineal Hernia After Robotic Abdominoperineal Resection: A Single‐Center, Retrospective Cohort Study

Annals of Gastroenterological Surgery, EarlyView.
This study aimed to investigate the safety and efficacy of pelvic reinforcement procedure (PRP) in robotic abdominoperineal resection (Ro‐APR). PRP‐ had a significantly higher rate of imaged perineal hernia (PH) (39.2% vs. 6.7%, p = 0.005) and symptomatic PH (19.6% vs.
Yoshihiro Sakai, Shunsuke Kasai, Akio Shiomi, Shoichi Manabe, Yusuke Yamaoka, Yusuke Tanaka, Takahiro Igaki, Hiroyasu Kagawa, Yusuke Kinugasa   +8 more
wiley   +1 more source