Results 71 to 80 of about 86,908 (330)

Timing of recurrences of TEM resected rectal neoplasms is variable as per the surveillance practices of one tertiary care institution [PDF]

, 2021
Allison Keeping, Paul M. Johnson, Christopher Kenyon, Katerina Neumann   +3 more
openalex   +1 more source

Cancer Cells Traverse Faster in Confined Space by Modifying Vimentin filaments With Nuclear Deformation and Promoting the Growth of Desired Tumor Spheroids

Advanced Materials Interfaces, EarlyView.
This study demonstrates how the Vimentin intermediate (VIM) filaments distribution/density regulates the attainment of different migration modes through cytoskeleton rearrangement and controls the nuclear morphology in migrating cells under physical confinement, which facilitates the faster traversing of those cells and the growth of post‐migration ...
Md Kowsar Alam, Jiao Zhai, Heng Zou, Yu Chen, Michael Yang   +4 more
wiley   +1 more source

Pre-referral GP consultations in patients subsequently diagnosed with rarer cancers: a study of patient-reported data. [PDF]

, 2016
BACKGROUND: Some patients with cancer experience multiple pre-diagnostic consultations in primary care, leading to longer time intervals to specialist investigations and diagnosis.
Abel, GA, Lyratzopoulos, G, Mendonca, SC
core   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

Methodological and Reporting Quality of Comparative Studies Evaluating Health-Related Quality of Life of Colorectal Cancer Patients and Controls: A Systematic Review [PDF]

, 2016
BACKGROUND: Health-related quality of life is an important outcome measure in patients with colorectal cancer. Comparison with normative data has been increasingly undertaken to assess the additional impact of colorectal cancer on health-related quality ...
Chen, J, Guo, Y, Lam, CLK, Wong, CKH
core   +1 more source

Rectal stromal tumor with an exceptional liver and bone metastatic locations

The Pan African Medical Journal, 2019
Gastrointestinal stromal tumours (GIST) are rare mesenchymal tumours which represent 1% to 3% of gastrointestinal neoplasm. Rectal location of GIST is extremely rare reaching 5% of GIST and only 0.1% of rectal tumours.
Dougaz Mohamed Wejih, Gouta Esma Leila, Chaouch Mohamed Ali, Nouira Ramzi, Bouasker Ibtissem, Dziri Chadli   +5 more
doaj   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Molecular testing for Lynch syndrome in people with colorectal cancer: systematic reviews and economic evaluation [PDF]

, 2017
This is the final version of the article. Available from the publisher via the DOI in this record.BACKGROUND: Inherited mutations in deoxyribonucleic acid (DNA) mismatch repair (MMR) genes lead to an increased risk of colorectal cancer (CRC ...
Aarnio, Ahadova, Arends, Balmana, Barnetson, Barrow, Barrow, Barrow, Barzi, Boland, Bonadona, Bonis, Bouzourene, Bowel Cancer UK, Burn, Cairns, Caldes, Calvert, Cancer Research, Cancer Research UK, Cancer Research UK, Centre for Reviews and Dissemination, Chang, Chen, Colling, Commercial Medicines Unit, Curtis, Curtis, Cuzick, de Boer, Department of Health, Desouza, Dietmaier, Dineen, Dinh, Doble, Dolan, Domingo, Dove-Edwin, Drummond, East of Scotland Regional Genetic Service, Eccleston, Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Working Group, Evers, Fajobi, Ferrandina, Finan, Frayling, Färkkilä, Gallego, Gallego, Gallego, Gavin, George, Giardiello, Goker, Goldstein, Great Britain, Grosse, Haanstra, Hall, Hampel, Hampel, Hanly, Haraldsdottir, Haraldsdottir, Havrilesky, Hendriks, Hildebrandt, Hornbrook, Hung, Ibrahim, Janus, Jenkins, John, Joint Formulary Committee, Järvinen, Järvinen, Kalady, Kaur, Kempers, Kloor, Kuppermann, Labianca, Ladabaum, Ladabaum, Le, Lewin, Ligtenberg, Lijmer, Limburg, Lin, Longworth, Loughrey, Lynch, Maeda, Mecklin, Mhaidat, Mittmann, Moher, Morak, Mueller, Mulder, Munoz, Mvundura, Møller, Møller, National Cancer Intelligence Network, National Cancer Intelligence Network, National Comprehensive Cancer Network, National Institute for Health and Care Excellence, National Institute for Health and Care Excellence, National Institute for Health and Care Excellence, National Institute for Health and Care Excellence, National Institute for Health and Care Excellence, National Institute for Health and Care Excellence, Ness, Newton, NHS, NHS Prescription Services, Niessen, Niv, Nout, Office for National Statistics, Office for National Statistics, Office for National Statistics, Office for National Statistics, Office for National Statistics, Office for National Statistics, Office for National Statistics, Office for National Statistics, Office for National Statistics, Office for National Statistics, Office for National Statistics, Office for National Statistics, Office for National Statistics, Office for National Statistics, Office for National Statistics, Office for National Statistics, Okkels, Overbeek, Overbeek, Palomaki, Pande, Parsons, Pawlik, Peninsula Technology Assessment Group (PenTAG), Philips, Pollett, Poulogiannis, Poynter, Ramsey, Ramsey, Ransohoff, Renkonen-Sinisalo, Sacco, Schmeler, Schnell, Senter, Severin, Sharp, Shia, Shlien, Sjursen, Sjursen, Slade, Snowsill, Snowsill, Southey, Stein, Sundar, The Stationery Office, Thompson, Thong, Trueman, UK Genetic Testing Network, Umar, US National Library of Medicine, Vasen, Vasen, Vasen, Vasen, Veysey, Wang, Ward, Webber, Welsh Cancer Intelligence and Surveillance Unit, Whiting, Whiting, Whiting, Wong, Wong, Wong, Zhang   +193 more
core   +2 more sources

Management of the rectal cancer early diagnostics improvement by «Onkopatrul» and quality of medical care improvement with intraoperative radiation

Кубанский научный медицинский вестник, 2014
In the article we observed the rectal cancer morbidity and mortality rate in Krasnodar region in comparison with median Russian Federation rates. The results of the preventive «Onkopatrul» project for rectal cancer early diagnostics were carried out.
M. V. Kazantseva
doaj  

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source