Results 101 to 110 of about 582,867 (329)

Anorectal Malignant Melanoma Post- Hemorrhoidectomy

Acta Médica Portuguesa
Anorectal malignant melanoma, a rare and aggressive tumor, lacks specific symptoms and frequently presents diagnostic challenges due to its similarity to benign anorectal conditions.
Ramazan Kozan, Ozkan Akpinar, Meral Toker   +2 more
doaj   +1 more source

Potentially paraneoplastic glomerulopathies in a Brazilian cohort: a retrospective analysis [PDF]

Brazilian Journal of Nephrology
Introduction: Glomerular diseases can be associated with solid or hematopoietic malignancies. The prevalence of these associations varies according to the studied glomerular disease.
Marcella Soares Laferreira, Gianna Mastroianni Kirsztajn   +1 more
doaj   +1 more source

Characterization and prognostic value of mutations in exons 5 and 6 of the p53 gene in patients with colorectal cancers in central Iran [PDF]

, 2013
Background/Aims: We aimed to investigate the relation-ships among various mutations of the p53 gene and their protein products, histological characteristics, and disease prognosis of primary colorectal cancer in Isfahan, central Iran.
Anwar, Bazan, Carson, Chang, Chang, Coombs, Cunningham, Derakhshan, Diez, Duffy, Erster, Gryfe, Hollstein, Jemal, Karsa, Kato, Lam, Leahy, Levine, Lim, Mahdavinia, Markowitz, Mehdi Nikbakht, Mohammad H. Derakhshan, Mohammad J. Namazi, Mohammad Salehi, Molleví, Mousavi, Munro, Nasierowska-Guttmejer, Nunes, Pan, Rahim Golmohammadi, Rogel, Russo, Ryan, Sadjadi, Schmitt, Slattery, Tang, Theodoropoulos, Tominaga, Vogelstein, Yamashita, Yee, Zhang, Zhao   +46 more
core   +1 more source

Onion‐Mitochondria Inhibit Lipopolysaccharide‐Induced Acute Lung Injury by Shaping Lung Macrophage Mitochondrial Function

Advanced Science, EarlyView.
Proposed model of orally administered onion mitochondria (O‐Mit) uptake by lung macrophages and fuse with macrophage mitochondria (M‐Mit). This fusion reprograms the metabolism of dysfunctional M‐Mit in lipopolysaccharide‐induced murine acute lung injury by modulating dynamin‐related protein 1 (DRP1) phosphorylation and cardiolipin peroxidation ...
Qingbo Xu, Yun Teng, Yinan Huang, Jingyao Mu, Lucy Teng, Hongjia Qian, Qiming Huang, Minmin Liu, Yi Zou, Lifeng Zhang, Michael L Merchant, Xiang Zhang, Jun Yan, Huang‐Ge Zhang   +13 more
wiley   +1 more source

Socioeconomic Indicators, Tobacco and Alcohol in the Aetiology of Digestive Tract Neoplasms [PDF]

, 2017
Ferraroni M {Institute of Medical Statistics, University of Milan, 20133 Milan, Italy), Negri E, La Vecchia C, D'Avanzo B and Franceschi S. Socioeconomic indicators, tobacco and alcohol in the aetiology of digestive tract neoplasms. International Journal
D'AVANZO, BARBARA, FERRARONI, MONICA, FRANCESCHI, SILVIA, NEGRI, EVA, VECCHIA, CARLO LA   +4 more
core  

Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants. [PDF]

, 2013
A locus on human chromosome 11q23 tagged by marker rs3802842 was associated with colorectal cancer (CRC) in a genome-wide association study; this finding has been replicated in case-control studies worldwide. In order to identify biologic factors at this
Ash, Colleen, Beck, Timothy, Bielecki, Ryszard, Boutros, Paul C, Chan-Seng-Yue, Michelle, Chong, Taryne, D'Souza, David JA, De Borja, Richard, Dick, John E, Gallinger, Steven, Gryfe, Robert, Hodgson, Lyndsey, Hudson, Thomas J, Kozak, Krystian, Kwan, Jennifer YY, Lee, Shawna, Lemire, Mathieu, McPherson, John D, Peltekova, Vanya D, Pollett, Aaron, Qazi, Aamer M, Rangrej, Jagadish, Rogers, Marianne, Stein, Lincoln D, Timms, Lee, Trinh, Quang M, Volar, Milica, Wang, Jianxin, Wang, Mike, Zaidi, Syed HE, Zandi, Sasan, Zanke, Brent W   +31 more
core   +2 more sources

Vinburnine Sensitizes Radiotherapy Efficacy in Nasopharyngeal Carcinoma by Triggering Pyroptosis and Immune Responses via Activation of EDAR‐NFκB Pathway

Advanced Science, EarlyView.
This study demonstrates that vinburnine, an approved cerebrovascular drug, synergizes with radiotherapy in nasopharyngeal carcinoma (NPC) by modulating EDAR‐NFκB signaling through directly binding to EDAR, leading to triggering apoptosis/pyroptosis, and amplifying CCL5/CX3CL1‐driven T‐cell cytotoxicity.
Jing Chen, Nian Liu, Qian Tao, Jie Wu, Jinyu Huang, Can Lu, Qiuqiu Li, Liangfang Shen, Xiang Chen, Cong Peng   +9 more
wiley   +1 more source

Rare rectal elastofibroma: diagnostic challenges and case report

Discover Oncology
Elastofibroma (EF) is a rare soft tissue tumor that typically occurs in the scapular region, with its occurrence in the rectum being extremely uncommon.
Chen-Xin Xiang, Yu Long, Yi-Ning Xiang, Fei Huang, Yun Ke, Yi-Ran Yao, Yun-Huan Zhen   +6 more
doaj   +1 more source

P53 mutations in human adrenocortical neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms have not been elucidated as yet. However, loss of heterozygosity at chromosomal locus 17p has been consistently observed in adrenocortical cancer.
Allolio, B., Chrousos, G. P., Karl, M., Linehan, M., Mastorakis, G., Reincke, Martin, Travis, W.   +6 more
core  

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source