Results 261 to 270 of about 104,894 (342)

Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease

Journal of Periodontology, EarlyView.
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar, Jeba Mercy Gnanasekaran, Niyant Ganesh, Cindy Zhou, Amy Plotkin, Giacomo Baima, Massimo Costalonga, Fenfen Zhou, Hanping Feng, Priyam Jani, Jean‐Pierre Raufman, Vivek Thumbigere‐Math   +11 more
wiley   +1 more source

Evaluating MRI response criteria in microsatellite instability-high rectal cancer treated with immune checkpoint inhibitors. [PDF]

ESMO Open
Vanderbecq Q, Cohen R, Camus M, Dray X, Parc Y, André T, Wagner M.   +6 more
europepmc   +1 more source

Reshaping study design for faster extrapolation‐based drug approval in pediatric inflammatory bowel diseases: An ESPGHAN–NASPGHAN position paper

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Children with inflammatory bowel diseases (IBD) have limited access to the available advanced therapies, given the lengthy gap between adult and pediatric approval. We aimed to review key hurdles for pediatric trials and recommend practical solutions.
Dan Turner, Amit Assa, Mikkel Malham, Shira Yuval Bar‐Asher, Carla Rayan, Jeffrey S. Hyams, Holm H. Uhlig, Brad Pasternak, David C. Wilson, Hilary K. Michel, Lissy de Ridder, Eric Zuckerman, Marina Aloi, Peter Szitanyi, Marla C. Dubinsky, Anne M. Griffiths, Roberto Saldana, Javier Martín‐de‐Carpi, Eytan Wine, Richard K. Russell, Jeremy Adler, Joseph Picoraro   +21 more
wiley   +1 more source

Gastrointestinal stromal tumor of the rectum mimicking a prostatic mass: case report. [PDF]

Radiol Case Rep
El Hajjami A, Bouktib Y, Boutakioute B, Ouali Idrissi M, Cherif Idrissi Elganouni N.   +4 more
europepmc   +1 more source

Real‐world data on STRIDE‐II treatment targets in a pediatric cohort with inflammatory bowel disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives STRIDE (selecting therapeutic targets in inflammatory bowel disease) established evidence‐based targets for treat‐to‐target strategies in IBD. STRIDE‐II designates clinical remission, C‐reactive protein (CRP) normalization, and fecal calprotectin (FC) reduction as short‐ to intermediate‐term targets, and mucosal healing as a long ...
Marie‐Luise Frank, Thu Giang Le Thi, Ina Schacker, Lena Bragagna, Milena Geist, Simon Buehler, Victoria Riedl, Sibylle Koletzko, Tobias Schwerd, Hannes Hoelz   +9 more
wiley   +1 more source

Semi-automatic evaluation of lymph nodes in patients with rectal neoplasms with diffusion weighted MRI

, 2016
Daniel Roth
openalex   +1 more source

Perioperative utilization of JAK inhibitors in Perianal Fistulizing Crohn's disease

JPGN Reports, EarlyView.
Abstract With the recent approval of small molecule drugs such as upadacitinib in adult inflammatory bowel disease (IBD), their utilization is becoming more common; however, there is limited data on perioperative risks or optimal timing of cessation and resumption to mitigate flares. Current recommendations suggest holding these medications for 14 days
Alexander Lyons, Lindsey Lawrence, Samantha Saul   +2 more
wiley   +1 more source

Successful Management of Recurrent Rectal Leiomyosarcoma: A Case Report. [PDF]

Clin Case Rep
Butare A, Akram W.
europepmc   +1 more source

Impact of timing on mucosal healing during restaging endoscopy in pediatric Crohn's disease: A retrospective cohort study

JPGN Reports, EarlyView.
Abstract While endoscopic remission is an important target in pediatric Crohn's disease (CD), no consensus for restaging timing exists. This retrospective cohort study assessed the timing and impact of restaging endoscopy in children with new CD in remission, comparing earlier ( ≤ 9 months) versus later endoscopy.
Anna Janecek, Alexandra S. Hudson, David L. Suskind, Hengqi B. Zheng, Samuel Simpson, Dale Lee, Ghassan Wahbeh, Hannibal Person   +7 more
wiley   +1 more source

Fournier's gangrene as initial presentation of rectal cancer. [PDF]

J Surg Case Rep
Sánchez Iglesias S, de la Cruz Cuadrado C, de Pedro Conal J.   +2 more
europepmc   +1 more source