Results 271 to 280 of about 549,282 (362)

Coexistence of APC and KRAS Mutations in Familial Adenomatous Polyposis and Endometrial Cancer: A Mini‐Review With Case‐Based Perspective

open access: yesMed Research, EarlyView.
ABSTRACT Familial adenomatous polyposis (FAP) is a well‐characterized hereditary colorectal cancer syndrome driven by germline mutations in the APC gene. KRAS mutations, although more common in sporadic colorectal and endometrial cancers, are rarely seen concurrently in patients with FAP.
Tongchuan Yin   +4 more
wiley   +1 more source

Current Application Status and Innovative Development of Surgical Robot

open access: yesMed Research, EarlyView.
Advantage, Challenge and Innovation of surgical robots. ABSTRACT Surgery has undergone a revolutionary development since the innovations in anesthesiology, aseptic techniques, and antibiotics. The use of modern techniques, especially minimally invasive techniques, has led to a new era of microsurgery and reduced patient trauma.
Aimin Jiang   +11 more
wiley   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Decoding Gene Expression Changes in Cerebral Tumors: Before and After Radiotherapy

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Cerebral tumors, particularly in pediatric patients, pose a significant challenge in oncology. Radiotherapy is a crucial component of the multimodal treatment approach for these tumors. Understanding the molecular basis of these tumors, particularly their response to radiotherapy, is crucial for improving treatment outcomes and patient ...
Ahana Maitra   +9 more
wiley   +1 more source

Radiomics‐Based CT Prediction of KRAS/NRAS/BRAF Mutation Status in Colorectal Cancer: A Multicenter Study

open access: yesMedicine Advances, EarlyView.
We developed a CT radiomics‐based model to predict KRAS/NRAS/BRAF mutations in colorectal cancer. A multicenter retrospective study integrated LASSO‐selected features and clinical data to build a combined model. CT radiomics can aid gene status prediction, supporting personalized treatment.
Yinrui Yang   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy