Results 41 to 50 of about 280,810 (293)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

The role of rectal hyposensitivity in the development of functional hindgut disorders: clinical significance and pathophysiology [PDF]

open access: yes, 2014
The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without the prior written consent of the authorBackground Rectal hyposensitivity (RH) is associated with functional hindgut ...
Burgell, Rebecca Elizabeth
core   +2 more sources

Pathological Complete Response in a Rare Case of Rectal Small Cell Neuroendocrine Carcinoma Following Neoadjuvant Radiochemotherapy: A Case Report

open access: yesClinical Case Reports
Rectal neuroendocrine neoplasms are rare, aggressive tumors comprising a small fraction of rectal malignancies but with increasing incidence due to improved endoscopic detection.
Abhisek Jha   +8 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

The evaluation of the benefit of a nurse led rectal bleeder clinic [PDF]

open access: yes, 2022
Rectal bleeding is a common referral symptom to colorectal services. In a small percentage of people it can be a recognised symptom of bowel cancer warranting further investigation.

core   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

Laparoscopy and loop colostomy : a new approach to extra-peritoneal rectal injuries [PDF]

open access: yes, 2003
Includes bibliographical references.Distal rectal washout and presacral drainage appear to have little or no influence on the morbidity and mortality in patients with low-energy trauma to the rectum.
Navsaria, Pradeep H
core   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

Balloon-occluded retrograde glue embolization for intractable lymphorrhea from bilateral iliac lymphatics following surgery for rectal cancer

open access: yesRadiology Case Reports, 2020
Lymphorrhea is a rare complication of rectal surgery. Although percutaneous embolization of thoracic or lymphatic ducts is now increasingly being reported for various types of lymphatic leakage, there are only sparse data on lymphatic interventions for ...
Shigeyoshi Soga, MD   +2 more
doaj   +1 more source

ROLE OF HEREDITARY FACTORS IN THE DEVELOPMENT OF GLIAL BRAIN TUMORS

open access: yesŽurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2018
Background. The analysis data on the malignant neoplasms incidence among first-degree relatives of probands with glial brain tumors are presented. Goal.
Pashkevich A. M.   +2 more
doaj   +1 more source

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