Results 51 to 60 of about 263,943 (292)
Spontaneous regression of a rectal tonsil presenting as a large submucosal tumor
DEN Open, 2022 Rectal tonsils are localized hyperplastic lymphoid tissues in the rectum, and the initial endoscopic findings are consistent with those for neoplastic lesions. However, rectal tonsils are benign entities, and the diagnosis should be made cautiously. A 70‐
Toru Matsui +6 more
doaj +1 more source
Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties
Advanced Science, EarlyView.Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez +16 more
wiley +1 more source
Approach of Colorectal Surgeons to Lower Rectal Adenocarcinomas: Results from the Turkish Society of Colon and Rectal Surgery Database [PDF]
Aim: This study aimed to analyze surgical preferences and outcomes among patients with lower rectal tumors in Türkiye using data from the national Colorectal Cancer Database of the Turkish Society of Colon and Rectal Surgery (TSCRS).
Mehmet Ali Koç +3 more
core +1 more source
Advanced Science, EarlyView.An RVG‑engineered exosomal saRNA delivery system (RVG‑EVs‑saPtpro) effectively targets and activates hippocampal PTPRO, functioning as a “molecular brake” to alleviate cancer therapy‑related cognitive impairment (CTRCI) by enhancing neuronal survival, neurogenesis, and synaptic plasticity.
Zhimeng Yao +18 more
wiley +1 more source
Rectal Microbicides: Investments and Advocacy [PDF]
, 2006 The first-ever report tracking rectal microbicide research and development expenditures, was released on April 24 by the International Rectal Microbicide Working Group (IRMWG) at a special symposium titled "Rectal Microbicides - A New Frontier in HIV ...
Cindra Feuer
core +2 more sources
TAMIS: New Horizons in Modern Colorectal Surgery
Turkish Journal of Colorectal DiseaseTransanal minimally invasive surgery (TAMIS) has emerged as a major advancement in the management of rectal neoplasms. Building upon the principles of transanal endoscopic microsurgery (TEM), TAMIS provides a cost-effective and more accessible ...
Nurhilal Kızıltoprak +3 more
doaj +1 more source
Voiding Dysfunction after Total Mesorectal Excision in Rectal Cancer [PDF]
International Neurourology Journal, 2011 Purpose The aim of this study was to assess the voiding dysfunction after rectal cancer surgery with total mesorectal excision (TME). Methods This was part of a prospective study done in the rectal cancer patients who underwent surgery with TME between ...
Jae Heon Kim +7 more
doaj +1 more source
Phase II trial of preoperative radiochemotherapy with concurrent bevacizumab, capecitabine and oxaliplatin in patients with locally advanced rectal cancer [PDF]
, 2013 Background: Preoperative radiochemotherapy (RCT) with 5-FU or capecitabine is the standard of care for patients with locally advanced rectal cancer (LARC). Preoperative RCT achieves pathological complete response rates (pCR) of 10-15%.
Erik Engel +19 more
core +1 more source
Advanced Science, EarlyView.Metastasis remains a major challenge in colorectal cancer. Using an in vivo shRNA screening system, this study identifies Homeobox D4 as a key metastasis suppressor. Reduced Homeobox D4 expression is associated with aggressive tumor features. Functional and mechanistic analyses show that it inhibits epithelial‐mesenchymal transition by repressing ...
Zhi‐hua Ye +9 more
wiley +1 more source