Results 111 to 120 of about 6,487,043 (364)
Background The antipyretic effectiveness of rectal versus oral acetaminophen is not well established. This study is designed to compare the antipyretic effectiveness of two rectal acetaminophen doses (15 mg/kg) and (35 mg/kg), to the standard oral dose ...
Malaeb Shadi+6 more
doaj +1 more source
Determining predictors of underlying etiology and clinical deterioration in patients with physiologic instability in the emergency department [PDF]
Thesis (M.A.)--Boston UniversityShock is a critical state defined by inadequate oxygen delivery to tissues. It is well known in the critical care community that early diagnosis and treatment of shock are crucial to improving patient outcomes. However, in
Day, Danielle E.
core +1 more source
An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou+30 more
wiley +1 more source
Faecal haemoglobin and faecal calprotectin as indicators of bowel disease in patients presenting to primary care with bowel symptoms [PDF]
OBJECTIVE: In primary care, assessing which patients with bowel symptoms harbour significant disease (cancer, higher-risk adenoma or IBD) is difficult.
Allison+32 more
core +3 more sources
7‐KDCA functions by driving intestinal epithelial cell migration through induction of calcium release from the endoplasmic reticulum. The findings emphasize a previously unrecognized property of 7‐KDCA in regulating cell migration, a required process for effective epithelial restitution and repair that is particularly critical for patients with UC to ...
Jing Zhang+9 more
wiley +1 more source
Assessed Temperatures and Stress in Cats Using Tympanic and Rectal Thermometers
Previous studies using tympanic thermometers on pets have presented inconsistent conclusions. The first aim of the current study was to compare the assessed temperatures using tympanic and rectal thermometers on healthy cats in a home environment and in ...
Yrla Hanström+5 more
doaj +1 more source
Impaired thermoregulatory function during dynamic exercise in multiple sclerosis [PDF]
INTRODUCTION: Impairments in sudomotor function during passive whole-body heating have been reported in multiple sclerosis (MS), a demyelinating disease of the CNS that disrupts autonomic function.
Allen, Dustin+5 more
core +1 more source
Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension
H4R and its downstream TRPV1 channel mediate the excitatory effect of TMN histaminergic afferent inputs on GABAergic sympathoinhibitory neurons in RVMM. Intranasal delivery of selective H4R agonist VUF 8430 suppresses renal sympathetic outflow and elicits sustained depressor and bradycardia responses in SHRs and CUMS‐induced hypertensive rats ...
Ying Shi+18 more
wiley +1 more source