Results 121 to 130 of about 6,487,043 (364)

Brain serotonin and dopamine modulators, perceptual responses and endurance performance during exercise in the heat following creatine supplementation [PDF]

, 2008
Background:The present experiment examined the responses of peripheral modulators and indices of brain serotonin (5-HT) and dopamine (DA) function and their association with perception of effort during prolonged exercise in the heat after creatine (Cr ...
Hadjicharalambous, M., Kilduff, L., Pitsiladis, Y.P.   +2 more
core   +3 more sources

A Porcine Monoclonal Antibody Targeting a Conserved GP4 Epitope Protects against In Vivo Infection via the Induction of Broad‐Spectrum PRRSV Neutralization

Advanced Science, EarlyView.
This study developed mAb‐5F2, a monoclonal antibody targeting conserved GP4 residues (Q48/I50), which blocks the GP4‐CD163 interaction, resulting in a 78–85% reduction in viral entry. Porcineized 5F2‐pFc prevented mortality in infected piglets, reduced pulmonary viral loads, and minimized lesions. This broad‐spectrum antibody platform overcomes vaccine
Xu Chen, Jiakai Zhao, Pinpin Ji, Xiaoxuan Li, Hui Niu, Dian Jiao, Lu Zhang, Qianyi Zhu, Xinyu Liu, Julian A. Hiscox, James P. Stewart, Yani Sun, Qin Zhao   +12 more
wiley   +1 more source

Fall in Rectal Temperature as an Indication of Anaphylactic Shock in the Mouse [PDF]

, 1955
Leon S. Kind
openalex   +1 more source

Effects of pre-transport fasting on the physiological responses of young cattle to 8-hour road transport [PDF]

, 2006
peer-reviewedThe effects of fasting animals for 8 h prior to an 8-h road journey and their ability to cope with the stress of transport were investigated. The treatments were: 1) fasted and then transported (n=20); 2) non-fasted and transported (n=18); 3)
Earley, Bernadette, Fisher, A.D., O'Riordan, Edward G.   +2 more
core  

Stabilisation of Na,K-ATPase structure by the cardiotonic steroid ouabain [PDF]

, 2013
Cardiotonic steroids such as ouabain bind with high affinity to the membrane-bound cation-transporting P-type Na,K-ATPase, leading to complete inhibition of the enzyme.
Abdul-Gader, Andrew J. Miles, B.A. Wallace, Esmann, Esmann, Esmann, Esmann, Fedosova, Kabsch, Kaplan, Klodos, Klose, Lees, Lowry, Mikael Esmann, Miles, Miles, Miles, Miles, Morth, Natalya U. Fedosova, Ogawa, Provencher, Schoner, Shinoda, Skou, Sreerama, Søren V. Hoffmann, Van Stokkum, Whitmore, Yatime   +30 more
core   +1 more source

Secondary Bile Acids Modified by Odoribacter Splanchnicus Alleviate Colitis by Suppressing Neutrophil Extracellular Trap Formation

Advanced Science, EarlyView.
In ulcerative colitis, the loss of Odoribacter splanchnicus disrupts a microbiota‐metabolite‐neutrophil axis. Restoring this bacterium boosts lithocholic acid, which suppress neutrophil extracellular trap formation and eases colonic inflammation.
Jing Xu, Jianhong Li, Xue Guo, Chen Huang, Yao Peng, Haoming Xu, Yingfei Li, Jingkui Xu, Jinxia Hu, Yitong Liao, Yuqiang Nie, Youlian Zhou   +11 more
wiley   +1 more source

Neurophilic Biomimetic Lipoprotein‐Mediated Targeted Nerve Growth Factor Delivery for Traumatic Brain Injury Therapy

Advanced Science, EarlyView.
Design of neurophilic biomimetic lipoprotein for intracerebral delivery of nerve growth factor (NGF) to traumatic brain injury (TBI). Nc‐rHDL@P can cross the BBB through ApoE3‐receptors interaction and target neurons via αRDP‐nAChR interaction. Nc‐rHDL@P delivers NGF to the lesion sites, rescues neurons, curbs inflammation, boosts sensorimotor and ...
Jialin Huang, Wenye Wang, Yidong Peng, Weiji Weng, Hanyu Wei, Qiyuan Feng, Antian Wang, Minjie Hu, Zhuoran Li, Shenyu Sun, Zhenghui He, Daiwen Zhang, Wenlan Qi, Yuhan Han, Zixuan Ma, Jiyuan Hui, Ru Gong, Yingwei Gao, Yong Lin, Jiyao Jiang, Xiaoling Gao, Junfeng Feng   +21 more
wiley   +1 more source

A Charge‐Adhesive Targeted DNA Gel Bandage for the Precision Treatment of Inflammatory Bowel Disease

Advanced Science, EarlyView.
DNA gel bandage (DNAgb) is designed to precisely target the site of inflammation of IBD, by achieving dual specific localization of inflamed mucosa through electrostatic interactions and ApITGA4‐mediated affinity targeting. DNAgb effectively the activation of inflammatory pathways and reshapes the immune microenvironment.
Peifen Lu, Hongxiu Yuan, Gang Wang, Tao Cheng, Lie Li, Yixi Dong, Runyu Zhao, Xuerui Zhang, Jianwei Jiao, Jin Jiao   +9 more
wiley   +1 more source

Comparison of Rectal, Axillary, Abdominal Skin and Tympanic Membrane Temperature Measurements in Term and Preterm Neonates

Siriraj Medical Journal, 1999
A quasi-experimenal study was conducted to investigate the optimum time and accuracy of temperature measurements from four sites: rectum (2.5 cm and 3 cm beyond the anus in preterm and term neonates, respectively), axilla (with mercury-in-glass ...
V Jirapaet, W Lerthamtewe
doaj  

Acclimatization to Cold in Antarctica as shown by Rectal Temperature Response to a Standard Cold Stress [PDF]

, 1962
G. M. Budd
openalex   +1 more source