Results 151 to 160 of about 5,081,991 (350)
The prognostic and therapeutic significance of biological molecular markers in human anorectal carcinomas treated with 5'fluorouracil chemoradiation. [PDF]
Advances in tumour biology have led to studies of new biological markers, which may predict treatment response and clinical outcome independently of standard clinicopathological variables.
Mawdsley, S.K.V.
core
This multicenter prospective study provides the first Japanese evidence that circumferential resection margin positivity after minimally invasive surgery is associated with poorer long‐term outcomes in locally advanced rectal cancer. As the cohort predominantly included patients treated with upfront surgery, these findings provide important evidence to
Atsushi Hamabe +19 more
wiley +1 more source
Background/Objectives: The tumor microenvironment (TME) has emerged as a significant prognostic factor. This study aimed to identify prognostic factors by combining clinicopathologic parameters and the TME biomarkers in patients who underwent surgery ...
Cho, Sang-Hee +23 more
core +1 more source
Sonography transmission gel as endorectal contrast agent for tumor visualization in rectal cancer
OBJECTIVE: The purpose of our study is to show the usefulness and safety of sonography transmission gel as an endorectal contrast agent in preoperative rectal MRI for tumor visualization in rectal cancer.
Lee, Jeong Min +5 more
core +1 more source
ABSTRACT Background Frailty predicts outcomes after colorectal cancer surgery, but postoperative changes remain unclear. We previously reported improvement in FRAIL Scale‐based frail/pre‐frail status 1 year after curative minimally invasive surgery (MIS).
Hajime Ushigome +9 more
wiley +1 more source
KRAS mutation demonstrated a prognostic impact according to primary tumor sidedness, independent of tumor morphology, in patients undergoing hepatectomy for colorectal liver metastases. A nomogram integrating biological and clinicopathological factors was developed to provide continuous biological risk assessment.
Yuzo Umeda +9 more
wiley +1 more source
ABSTRACT Aim Long‐term stoma‐free outcomes after diverting stoma closure in patients who underwent sphincter‐preserving rectal cancer surgery with double‐stapling technique (DST) reconstruction following radiation‐based neoadjuvant treatment remain unclear.
Hidetaka Ichikawa +7 more
wiley +1 more source
Abbreviated Abstract This nationwide retrospective cohort study of 5458 colorectal cancer surgeries across 32 Japanese institutions examined the effects of laparoscopic surgery, adhesion prevention materials (APMs), and stoma creation on the 5‐year risk of small bowel obstruction (SBO).
Takeshi Yamada +19 more
wiley +1 more source
ABSTRACT Immune checkpoint blockade (ICB) has transformed the treatment of mismatch repair‐deficient (dMMR) colorectal cancer but produces no meaningful benefit in advanced mismatch repair‐proficient (pMMR) disease. In the neoadjuvant setting, however, pathological responses have been reported in a subset of pMMR tumors, suggesting that clinical ...
Kimihiro Yamashita +4 more
wiley +1 more source
Rectal tumor fragmentation as a response pattern following chemoradiation. [PDF]
Mills MN +9 more
europepmc +1 more source

