Results 151 to 160 of about 5,081,991 (350)

The prognostic and therapeutic significance of biological molecular markers in human anorectal carcinomas treated with 5'fluorouracil chemoradiation. [PDF]

open access: yes, 2005
Advances in tumour biology have led to studies of new biological markers, which may predict treatment response and clinical outcome independently of standard clinicopathological variables.
Mawdsley, S.K.V.
core  

Prognostic Impact of Circumferential Resection Margin in Minimally Invasive Surgery for Locally Advanced Rectal Cancer: A Multicenter Prospective Study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This multicenter prospective study provides the first Japanese evidence that circumferential resection margin positivity after minimally invasive surgery is associated with poorer long‐term outcomes in locally advanced rectal cancer. As the cohort predominantly included patients treated with upfront surgery, these findings provide important evidence to
Atsushi Hamabe   +19 more
wiley   +1 more source

Tumor Immune Microenvironment Biomarkers for Recurrence Prediction in Locally Advanced Rectal Cancer Patients after Neoadjuvant Chemoradiotherapy

open access: yes
Background/Objectives: The tumor microenvironment (TME) has emerged as a significant prognostic factor. This study aimed to identify prognostic factors by combining clinicopathologic parameters and the TME biomarkers in patients who underwent surgery ...
Cho, Sang-Hee   +23 more
core   +1 more source

Sonography transmission gel as endorectal contrast agent for tumor visualization in rectal cancer

open access: yes, 2008
OBJECTIVE: The purpose of our study is to show the usefulness and safety of sonography transmission gel as an endorectal contrast agent in preoperative rectal MRI for tumor visualization in rectal cancer.
Lee, Jeong Min   +5 more
core   +1 more source

One‐Year Changes in Frailty Components After Curative Minimally Invasive Surgery for Colorectal Cancer in Older Patients

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Frailty predicts outcomes after colorectal cancer surgery, but postoperative changes remain unclear. We previously reported improvement in FRAIL Scale‐based frail/pre‐frail status 1 year after curative minimally invasive surgery (MIS).
Hajime Ushigome   +9 more
wiley   +1 more source

Biological Resectability in Colorectal Liver Metastases: A Nomogram‐Based Continuous Risk Model to Define Borderline Disease

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
KRAS mutation demonstrated a prognostic impact according to primary tumor sidedness, independent of tumor morphology, in patients undergoing hepatectomy for colorectal liver metastases. A nomogram integrating biological and clinicopathological factors was developed to provide continuous biological risk assessment.
Yuzo Umeda   +9 more
wiley   +1 more source

Long‐Term Stoma‐Free Outcomes After Diverting Stoma Closure Following Radiation‐Based Neoadjuvant Treatment for Rectal Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Long‐term stoma‐free outcomes after diverting stoma closure in patients who underwent sphincter‐preserving rectal cancer surgery with double‐stapling technique (DST) reconstruction following radiation‐based neoadjuvant treatment remain unclear.
Hidetaka Ichikawa   +7 more
wiley   +1 more source

Laparoscopic Surgery Is Associated With Reduced Small Bowel Obstruction Risk After Colorectal Cancer Surgery: A Nationwide Cohort Study of 5458 Patients

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Abbreviated Abstract This nationwide retrospective cohort study of 5458 colorectal cancer surgeries across 32 Japanese institutions examined the effects of laparoscopic surgery, adhesion prevention materials (APMs), and stoma creation on the 5‐year risk of small bowel obstruction (SBO).
Takeshi Yamada   +19 more
wiley   +1 more source

Can Chemoradiotherapy Expand Immune Checkpoint Blockade Responsiveness in Mismatch Repair‐Proficient Rectal Cancer?

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Immune checkpoint blockade (ICB) has transformed the treatment of mismatch repair‐deficient (dMMR) colorectal cancer but produces no meaningful benefit in advanced mismatch repair‐proficient (pMMR) disease. In the neoadjuvant setting, however, pathological responses have been reported in a subset of pMMR tumors, suggesting that clinical ...
Kimihiro Yamashita   +4 more
wiley   +1 more source

Rectal tumor fragmentation as a response pattern following chemoradiation. [PDF]

open access: yesJ Gastrointest Oncol, 2022
Mills MN   +9 more
europepmc   +1 more source

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