Results 161 to 170 of about 592,916 (287)

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

Advanced Science, EarlyView.
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen, Zhiquan Liu, Wenmin Wang, Qing Wang, Tia J. Kowal, Fan Zhang, Grzegorz Walkiewicz, Faruk Hossen, Herbert M. Lachman, Jinqiong Zhou, Yiting Wang, Yang Sun   +11 more
wiley   +1 more source

Atomistic insight into Al-Mg friction stir welding process via molecular dynamics simulation. [PDF]

PLoS One
Nguyen VT, Hoang VH, Nguyen TT, Thien TN, Vo XT, Nguyen VTT.   +5 more
europepmc   +1 more source

Self‐Sustaining Sensing Systems: Integration Strategies and Signal–Power Matching in Energy‐Harvesting Electronics

Advanced Science, EarlyView.
Energy‐harvesting‐integrated sensors couple ambient energy conversion with sensing, processing, and wireless communication. This review organizes recent progress through integration architectures and operating principles, revisiting co‐packaged, monolithic, and co‐functional designs together with always‐on, event‐driven, and multi‐modal sensing modes ...
Taehyun Park, Ki‐Yoon Park, Yeonho Choi, Dong‐Myeong Shin, Hong‐Joon Yoon, Hocheon Yoo   +5 more
wiley   +1 more source

Research on strengthening of T-shaped reinforced concrete simply supported beams with U-shaped jackets to enlarge the cross-section: Theoretical analysis, experiments, and finite element analysis. [PDF]

PLoS One
Wang JF, Bao EH, Zhou MS, Wu YS, Xiao CJ.   +4 more
europepmc   +1 more source

Palmitoyl Acyltransferase Zdhhc17 Promotes Functional Recovery After Spinal Cord Injury by Targeting the Nuclear Transport Factors Kpna2 and Ipo9

Advanced Science, EarlyView.
In this study, we demonstrate that Zdhhc17, acting as a PAT, suppresses neuronal apoptosis and promotes axon regeneration after injury, thereby enhancing functional recovery following SCI. In this context, Kpna2 and Ipo9 serve as novel palmitoylation substrates of Zdhhc17, whose palmitoylation prevents the injury‐induced degradation of their proteins ...
Meixuan Chen, Huan Chen, Sining Ding, Fan Liu, Xiaofei Zheng, Yuan Wang, Ruitu Tian, Huan Li, Peilin Liu, Le Hu, Bin Liu, Limin Rong, Mangmang Li   +12 more
wiley   +1 more source

Data-based surrogate modeling and performance prediction of MEMS touch mode capacitive sensing using deep multilayer perceptron networks. [PDF]

Front Artif Intell
E P, Jindal SK.
europepmc   +1 more source

Unveiling Anisotropic in‐Plane Thermal Conductivity and Thermal Expansion Coefficient in Low‐Symmetry Few‐Layer ReS2

Advanced Science, EarlyView.
Simultaneous two‐mode Raman thermometry reveals strong in‐plane anisotropic thermal conductivity and thermal expansion coefficients in low‐symmetry few‐layer ReS2. By decoupling thermal transport along the crystallographic a‐ and b‐axes within a single optical configuration, this study provides robust experimental evidence and ab initio theoretical ...
Manab Mandal, Prahalad Kanti Barman, Susmita Jana, Saroj Poudyal, Kaushalya Kumari, Sourav Mondal, Abhishek Misra, Birabar Ranjit Kumar Nanda, Pramoda Kumar Nayak, Kanikrishnan Sethupathi   +9 more
wiley   +1 more source

Experimental and 3D finite element modeling of line heating effect on thin mild steel sheets. [PDF]

Sci Rep
Kebede GA, Gutata GR, Abbera GH, Gemeda BD, Duressa CA.   +4 more
europepmc   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

Advanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen, Jiahui Lai, Qiongjiao Zeng, Liangbin Zhou, Boguang Yang, Bin Zhang, Min Wang, Jiajing Zhou, Kieran Lau, Khoon S. Lim, Zhong Alan Li, Rocky S. Tuan   +11 more
wiley   +1 more source

Analytical Analysis for a Uniformly Loaded Circular Plate of Functionally Graded Piezoelectric Materials Using Mian and Spencer Theory. [PDF]

Materials (Basel)
Fan H, Shen L, Zhu Z, Yang B.
europepmc   +1 more source