Results 141 to 150 of about 592,916 (287)
Advanced Science, EarlyView.A root‐inspired microneedle array patch uses lattice‐based mechanical interlocking to unite rigid microneedles with a flexible substrate. The interlocked rigid–soft architecture improves interfacial bonding, supports stable adhesion on curved and wet tissues under dynamic motion, and provides a versatile platform for robust biointerfacing and future ...
Jongchan Lee +9 more
wiley +1 more source
Advanced Science, EarlyView.This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu +10 more
wiley +1 more source
α‐Synuclein Forms Distinct Micelle‐Like Assemblies at Low Ionic Strengths
Advanced Science, EarlyView.At high ionic strength, α‐synuclein forms diverse assemblies, including oligomers, fibrils, and condensates. Here, we show that at low ionic strength, α‐synuclein adopts a distinct, low‐abundance assembly state. These assemblies maintain a constant size above a critical concentration and do not coalesce, suggesting a micelle‐like organization ...
Sophie Hertel +10 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu +10 more
wiley +1 more source
ZrCo3B2 and HfCo3B2 Electrodes Go on Stage for Oxygen Evolution Reaction
Advanced Science, EarlyView.The intermetallic compounds ZrCo3B2 and HfCo3B2 with distinctive chemical bonding features are excellent OER precursors, restructuring into OER‐active electrocatalysts delivering significantly high OER activities compared to the elemental Co, which is obvious from their lower onset potentials and increased obtained current densities.
Fatma Aras +4 more
wiley +1 more source
From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits
Advanced Science, EarlyView.This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang +5 more
wiley +1 more source
Advanced Science, EarlyView.A flexible, hexagonally packed artificial dielectric providing a wide range of effective permittivities (εr ≈ 30–1400) without lumped elements was developed for clinical and ultra‐high‐field MRI. Combined with modular passive‐dipole arrays, the system enables adaptable RF field shaping through electric‐ and magnetic‐dipole tuning.
Santosh Kumar Maurya +2 more
wiley +1 more source
Finite element analysis of the mechanical behavior of stiffened cold-formed built-up CFST flat columns. [PDF]
PLoS OneYu W, Wang H, Jiang Q, Wang H.
europepmc +1 more source
Advanced Science, EarlyView.A universal hydrogel microparticle template with five DNA‐addressable domains decouples particle fabrication from barcode writing. Contact‐free multilaminar flow lithography produces >106 templates/h, and post‐fabrication domain‐selective hybridization converts one batch into large, user‐defined optical barcode libraries with robust decoding and re ...
Akihiro Eguchi +5 more
wiley +1 more source
Buckling Analysis of Thin-Walled Laminated Plates Considering In-Plane and Out-of-Plane Coupling Effects Under Complex In-Plane Loads. [PDF]
Materials (Basel)Kolakowski Z, Teter A.
europepmc +1 more source