Results 101 to 110 of about 622,442 (395)

CD3+CD4+LAP+Foxp3-regulatory cells of the colonic lamina propria limit disease extension in ulcerative colitis [PDF]

, 2018
Background and Aims: In ulcerative colitis (UC), inflammation begins in the rectum and can extend proximally throughout the entire colon. The extension of inflammation is an important determinant of disease course, and may be limited by the action of ...
Amendola, Antonello, Boirivant, Monica, Borrini, Francesco, Butera, Alessia, De Nitto, Daniela, Di Carlo, Nazzareno, Frasca, Loredana, Lande, Roberto, Pica, Roberta, Pronio, Annamaria, Sanchez, Massimo   +10 more
core   +3 more sources

Prolapse of the Rectum [PDF]

Postgraduate Medical Journal, 1964
PROLAPSE of the rectum is a rare, somewhat misunderstood and neglected condition, which is generally held to occur at the extremes of life. XVe are almost totally ignorant of its cause. Misconceptions regarding its clinical presentation are common.
openaire   +3 more sources

Application of an interstitial and biodegradable balloon system for prostate-rectum separation during prostate cancer radiotherapy: a prospective multi-center study

Radiation Oncology, 2013
Rectal toxicity presents a significant limiting factor in prostate radiotherapy regimens. This study evaluated the safety and efficacy of an implantable and biodegradable balloon specifically designed to protect rectal tissue during radiotherapy by ...
E. Gez, S. Cytron, R. B. Yosef, D. London, B. Corn, S. Alani, G. Scarzello, Fabrizio Dal Moro, G. Sotti, F. Zattoni, I. Koziol, T. Torre, M. Bassignani, S. Kalnicki, R. Ghavamian, D. Blakaj, M. Anscher, M. Sommerauer, D. Jocham, Corinna Melchert, S. Huttenlocher, G. Kovacs, M. Garg   +22 more
semanticscholar   +1 more source

Single‐Cell Transcriptomics Unravels Growth Factor Erv1‐Like Mediated Ferroptosis as a Key Driver of Intestinal Epithelial Dysfunction in Ulcerative Colitis

Advanced Science, EarlyView.
Single‐cell transcriptomic profiling of ulcerative colitis (UC) tissues identified downregulation of GFER in intestinal epithelial cells. Mechanistically, GFER interacts with PCBP1 to help maintain intracellular iron homeostasis and may also reduce lipid peroxidation by activating the PGC‐1α/PPARγ signaling pathway, thereby inhibiting ferroptosis ...
Ya Song, Fangyan Tan, Qian Song, Xiaohui Liao, Zhechuan Mei, Lin Lv   +5 more
wiley   +1 more source

Anorectal Melanoma [PDF]

, 2018
Anorectal melanoma (AM) is a rare malignancy, characterized by aggressive behavior and a poor prognosis. AM is more frequent in female patients aged over 50 years.
Dario Didona, Giovanni Paolino, Giulia Macrì, Santo Raffaele Mercuri., Stefano Calvieri   +4 more
core   +1 more source

Definition of the rectum and level of the peritoneal reflection – still a matter of debate?

Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques, 2013
Introduction Pathological lesions of the rectum are common and their management requires detailed knowledge of pelvic anatomy. There has been considerable debate as to the definition of the rectum and the variability of the level of the peritoneal ...
J. Kenig, P. Richter
semanticscholar   +1 more source

Laser Ultrasound Super‐Resolution Imaging for Multi‐Parametric Non‐Invasive Volumetric Characterization of Brain Cancer

Advanced Science, EarlyView.
Laser ultrasound super‐resolution imaging (LUSSI) leverages laser‐generated ultrasound for functional 3D transcranial imaging of brain tumor vasculature. Combined with optoacoustic tomography, it is demonstrated in a glioblastoma model, revealing structural abnormalities, compressed vessels, hemorrhages, and hypoxic regions.
Daniil Nozdriukhin, Yi Chen, Shuxin Lyu, Daniel Razansky, Xosé Luís Deán‐Ben   +4 more
wiley   +1 more source

A study on the variation of bladder and rectal doses with respiration in intracavitary brachytherapy for cervix cancer

Journal of Contemporary Brachytherapy, 2010
Purpose: In cervical intracavitary brachytherapy, it is mandatory to evaluate if the doses to bladder and rectum are within tolerance limits. In this study, an effort has been made to evaluate the effect of respiration on the doses to bladder and rectum ...
Singh Karuna, Kunhi P Haresh, Pandjatcharam Jagadesan, Ramachandran Prabhakar, Pramod Kumar Julka, Goura Kishor Rath   +5 more
doaj  

Transanal minimally invasive surgery for rectal lesions [PDF]

, 2016
Background and Objectives: Transanal minimally invasive surgery (TAMIS) has emerged as an alternative to transanal endoscopic microsurgery (TEM). The authors report their experience with TAMIS for the treatment of mid and high rectal tumors.
Balla, Andrea, Di Lorenzo, Nicola, Franceschilli, Luana, Iafrate, Corrado, La Torre, Marco, Quaresima, Silvia, Shalaby, Mostafa, Sileri, Pierpaolo   +7 more
core   +1 more source

Calhm6 Governs Macrophage Polarization Through Chp1‐Camk4‐Creb1 Axis and Ectosomal Delivery in Inflammatory Responses

Advanced Science, EarlyView.
Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin, Xiaofan Xiong, Yan Zhang, Siyu Zhang, Shuting Zhang, Yu Yang, Yingxue Liang, Lulu Zang, Xi Chen, Wenjuan Li, Issam Halalmeh, Rui Zhou, Zongfang Li, Haowen Liu, Jing Geng   +14 more
wiley   +1 more source