Results 81 to 90 of about 539,390 (297)

Comparison of the prognostic value of tumour and patient related factors in patients undergoing potentially curative surgery for colon cancer [PDF]

, 2009
<b>Aim</b>: To comprehensively compare the prognostic value of tumour and patient-related factors in patients undergoing curative surgery for colon cancer.
Benson, Brown, Compton, Cooper, Crozier, Dukes, Forrest, Gabay, Gasser, Halazun, Hauser, Ishizuka, Kacevska, Kandemir, Kim, Kobayashi, Lee, Leitch, Lindmark, Maltoni, McMillan, McMillan, Mehrkhani, Michael, Moertel, Monreal, Morris, Petrelli, Ramsey, Roxburgh, Sasaki, Sharma, Smith, Taylor, Thynne, Vakkila, Vibert, Viganó, Walsh, Wanebo, Wang, Wolpin   +41 more
core   +1 more source

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

Disseminated lung cancer presenting as a rectal mass

European Clinical Respiratory Journal, 2016
Primary lung cancer is the leading cause of cancer-related deaths globally, and approximately 50% had metastatic disease at the time of diagnosis. A rectal mass and unintended weight loss are common manifestations of rectal cancer.
Mia M. Noergaard, Inger M. H. Stamp, Uffe Bodtger   +2 more
doaj   +1 more source

Candida carriage in the alimentary tract of liver transplant candidates [PDF]

, 1994
Thirty randomly selected patients with advanced chronic liver disease, which had been evaluated for possible liver transplantation, were sampled endoscopically at 7 alimentary tract locations to assess the frequency and amount of Candida carriage ...
Ho, M, Kusne, S, Pasculle, AW, Starzl, TE, Tobin, D, van Thiel, DH   +5 more
core   +1 more source

Diminished Signal‐to‐Noise Ratio Disrupts Somatosensory Population Encoding and Drives Tactile Hyposensitivity in the Fmr1−/y Autism Model

Advanced Science, EarlyView.
This study provides a translational approach for linking neural activity to tactile deficits in autism. By combining psychophysics with cortical recordings in a mouse model of autism, we show that low signal‐to‐noise ratio in somatosensory neurons weakens population encoding of fine touch, impairing detection, decoding, and leading to perceptual ...
Ourania Semelidou, Théo Gauvrit, Célien Vandromme, Alexandre Cornier, Anna Saint‐Jean, Yves Le Feuvre, Melanie Ginger, Andreas Frick   +7 more
wiley   +1 more source

Beads-on-String Model for Virtual Rectum Surgery Simulation [PDF]

A beads-on-string model is proposed to handle the deformation and collision of the rectum in virtual surgery simulation. The idea is firstly inspired by the observation of the similarity in shape shared by a rectum with regular bulges and a string of ...
Chang, Jian, Li, Wenxi, Pan, Junjun, Yang, Xiaosong, Zhang, Jian J.   +4 more
core  

Primary Signet-Ring Carcinoma (Linitus Plastica) of the Colorectum presenting as Subacute Intestinal Obstruction [PDF]

, 2012
Primary Signet-ring cell carcinoma (Linitus Plastica) of the colon and rectum is a rare form of adenocarcinoma of the large intestine and has been reported to have an extremely poor prognosis. We report a case of Primary Signet-ring cell carcinoma of the
Jagtap, SS, Jagtap, SV, Khirsagar, AY, Nikumbh, DB, S, Khan   +4 more
core  

High dose rate brachytherapy as monotherapy for localised prostate cancer : a hypofractionated two-implant approach in 351 consecutive patients [PDF]

, 2013
BACKGROUND: To report the clinical outcome of high dose rate brachytherapy as sole treatment for clinically localised prostate cancer. METHODS: Between March 2004 and January 2008, a total of 351 consecutive patients with clinically localised prostate ...
Baltas, Dimos, Chatzikonstantinou, Georgios, Milickovic, Natasa, Ratka, Markus, Tselis, Nikolaos, Tunn, Ulf W., Zamboglou, Nikolaos   +6 more
core   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

A study on the variation of bladder and rectal doses with respiration in intracavitary brachytherapy for cervix cancer

Journal of Contemporary Brachytherapy, 2010
Purpose: In cervical intracavitary brachytherapy, it is mandatory to evaluate if the doses to bladder and rectum are within tolerance limits. In this study, an effort has been made to evaluate the effect of respiration on the doses to bladder and rectum ...
Singh Karuna, Kunhi P Haresh, Pandjatcharam Jagadesan, Ramachandran Prabhakar, Pramod Kumar Julka, Goura Kishor Rath   +5 more
doaj