Results 141 to 150 of about 181,633 (341)
A NEW METHOD OF EXCISING THE TWO UPPER PORTIONS OF THE RECTUM AND THE LOWER SEGMENT OF THE SIGMOID FLEXURE OF THE COLON. [PDF]
Henry Maunsell
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This study reveals the tumor‐suppressive role of TRIM38 in colorectal cancer (CRC). TRIM38 is downregulated through DNA hypermethylation and correlates with unfavorable clinical features and poor prognosis. Mechanistically, TRIM38 inhibits CRC progression by promoting K48‐linked ubiquitination of CCT6A, leading to the destabilization of c‐Myc.
Yue Zhang+10 more
wiley +1 more source
A multi‐functional shear‐thinning hydrogel is engineered to treat enterocutaneous fistulas. This hydrogel can resist external pressures allowing it to remain within the fistula tract and is shown to have significant antimicrobial, pro‐healing, and anti‐inflammatory properties, which were validated in in vitro and in vivo experiments.
Jinjoo Kim+6 more
wiley +1 more source
Sexual dimorphism is a crucial aspect of mating and reproduction in many animals, yet the molecular mechanisms remain unclear. In Bactrocera dorsalis, sex pheromones trimethylpyrazine (TMP) and tetramethylpyrazine (TTMP) are specifically synthesized by ...
Jingxiang Chen+6 more
doaj +1 more source
MTCH2 Suppresses Thermogenesis by Regulating Autophagy in Adipose Tissue
This study demonstrates that MTCH2 acts as an evolutionarily conserved regulator of energy homeostasis across Drosophila, rodents, and humans. Adipose‐specific MTCH2 ablation enhances brown/beige adipose thermogenesis through Bcl‐2‐dependent autophagy, promoting energy expenditure and counteracting obesity‐associated metabolic disorders. These findings
Xin‐Yuan Zhao+17 more
wiley +1 more source
The Rectum in Gynæcology [PDF]
openaire +4 more sources
Annexin A3 (ANXA3) plays an endogenous protective role in endothelial dysfunction in sepsis by stabilizing the actin cytoskeleton, modulating cell permeability, and inhibiting pATF2/CD62E inflammatory signaling. Abstract Increased endothelial permeability and a dysregulated inflammatory response play key roles in organ damage in sepsis.
Manyu Xing+4 more
wiley +1 more source
ABDOMINOPERINEAL RESECTION OF THE RECTUM BY THE TWO-TEAM TECHNIC
W. B. Neal+4 more
openalex +2 more sources