Results 201 to 210 of about 395,349 (427)
Advanced Science, EarlyView.The RBR E3 ubiquitin ligase ARIH1, which is upregulated in colorectal cancer cells, promotes cell growth and metastasis and correlates with an unfavorable CRC prognosis. Mechanistically, ARIH1 catalyzes K63‐linked ubiquitination of PHB1, enhancing the interaction between PHB1 and Akt.
Ying Tong +13 more
wiley +1 more source
Gravitational waves from equatorially eccentric extreme mass ratio inspirals around swirling Kerr black holes [PDF]
arXivWe have studied the gravitational wave generated by extreme mass ratio inspirals (EMRIs) along eccentric orbits on equatorial plane within the frame of the swirling-Kerr black hole spacetime. The swirling-Kerr black hole has an extra swirling parameter, which characterizes the rotation of universe background.
arxiv
Advanced Science, EarlyView.The N1 peptide specifically targets neurons, enabling cytosolic delivery of fluorescent dyes and proteins for super‐resolution imaging and functional genetic modification. Abstract Efficient delivery of biomolecules into neurons has significant impacts on therapeutic applications in the central nervous system (CNS) and fundamental neuroscience research.
Xiaoqian Ge +16 more
wiley +1 more source
MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer
Advanced Science, EarlyView.This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang +9 more
wiley +1 more source
Specimen showing Carcinoma of the Pelvic Colon and Rectum co-existing and causing Acute Obstruction. [PDF]
, 1922 Charles Gordon‐Watson
openalex +1 more source
Surgical treatment of gastrointestinal stromal tumour of the rectum in the era of imatinib
British Journal of Surgery, 2015 M. Wilkinson +9 more
semanticscholar +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Advanced Science, EarlyView.Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang +4 more
wiley +1 more source
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2010 Aim of investigation. To study potential of application of up-to-date laser technique and new technologies at multistage method of surgical treatment of patients with high posttraumatic fistulas of rectum.Material and methods.
M. M. Mamedov, N. I. Mamedov
doaj