Results 211 to 220 of about 433,216 (318)

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source

Implementation of an AI-Driven Workflow for Daily Dose Reconstruction in Prostate Cancer Radiotherapy. [PDF]

Cancers (Basel)
Prunaretty J, Baudouin T, Riou O, Azria D, Fenoglietto P.   +4 more
europepmc   +1 more source

Pharmacometric evaluation of pre‐referral rectal artesunate in children with severe malaria

British Journal of Clinical Pharmacology, EarlyView.
Aims Parenteral artesunate is the preferred first‐line treatment for severe malaria. Pre‐referral rectal artesunate suppositories are recommended where parenteral treatment is inaccessible. In this study, we compared dihydroartemisinin exposure and model‐predicted early parasite clearance following rectal artesunate and intravenous artesunate in ...
Ayorinde Adehin, Marie A. Onyamboko, Caterina Fanello, Nicholas J. White, Nicholas P. J. Day, Richard M. Hoglund, Joel Tarning   +6 more
wiley   +1 more source

Determining the Correlation and Effect of Rectal and Bladder Volume Change in Shift of Planning Target Volume and Calculating Planning Target Volume Margin with Van Herk Formula in Prostate Cancer Tomotherapy. [PDF]

J Biomed Phys Eng
Shabaninejad V, Shanei A, Roayaei M, Akhavan A, Saeb M, Hadinezhad S.   +5 more
europepmc   +1 more source

Laparoscopic transabdominal approach for radical excision of low-lying presacral cyst: a case report and narrative mini-review. [PDF]

Front Oncol
Wang X, Liu M, Tan F, Li Y, Sun X.
europepmc   +1 more source

Glycopolymeric nanoparticles transported by activated platelets protect ischemic myocardium by alleviating PANoptosis through targeting macrophage Dectin‐1

BMEMat, EarlyView.
NP‐SF, designed to target macrophage Dectin‐1 and activated platelets, selectively accumulated in ischemic myocardium, where it was taken up by macrophages after platelet hitchhiking. By inhibiting NLRC5‐related PANoptosis, NP‐SF significantly attenuated pathological damage, and effectively preserved cardiac function in a murine ischemia–reperfusion ...
Guanye Yu, Na Yang, Yan Zhang, Lingxin Peng, Yi Li, Yue Chao, Qinfang Miao, Haikun Qi, Jianhui Zhuang, Weixia Jian, Bingyu Li, Wenhui Peng, Jinghua Chen, Shiyu Gong   +13 more
wiley   +1 more source

International disruptions to cancer diagnosis and stage at presentation during the COVID-19 pandemic in 2020: an International Cancer Benchmarking Partnership (ICBP) population-based study.

Lancet Oncol
Morgan E, Bardot A, Langselius O, Rutherford MJ, Elkader HA, Bennett D, Brennan A, Bucher O, Butler J, Cameron DA, Canfell K, Chiam K, Chiarelli A, Creighton N, De P, Evans S, Fitzpatrick D, Guren MG, Hannah J, Huws DW, Jackson CGCA, Kønig SM, Kumar E, Larønningen S, Lawler M, Liu Q, McClure C, Mehmood A, Mitchell H, Morrison DS, Murray D, Norwood T, Phillips KAM, Ransom D, Shack L, Smits S, Saint-Jacques N, Marvelde LT, Tran D, Turner D, Ursin G, Vernon S, Walker MJ, Woods RR, Zhang B, Bray F, Soerjomataram I.   +46 more
europepmc   +1 more source

Incarcerated Rectal Prolapse Secondary to Rectal Adenomatous Polyposis: A Case Report. [PDF]

Cureus
King AL, Okeke RI, Montgomery K, Landwehr F, Ismailov E, Underwood J, Grossman E, Ahmad S.   +7 more
europepmc   +1 more source

Lymphosarcoma of the Rectum [PDF]

Proceedings of the Royal Society of Medicine, 1961
openaire   +2 more sources

Autonomic Plexuses of the Female Sexual Organs Travel Within Pubocervical and Rectovaginal [Endopelvic] Fascia: A Rationale for ‘Nerve‐Aware’ Vaginal Prolapse Repair

Clinical Anatomy, EarlyView.
ABSTRACT The connective tissue support of female pelvic viscera—endopelvic fascia—has been studied in fetal and immunohistochemical models to demonstrate its relationship with the autonomic nerves of the female pelvis. Due to a paucity of literature examining the gross anatomical relationships between endopelvic fascia and autonomic nerves in adult ...
Stephen Magliocchetti, Benjamin Laxer, Leyla Spennato, Norah Alturki, Queena Chou, Tyler S. Beveridge   +5 more
wiley   +1 more source