Results 61 to 70 of about 1,636,890 (348)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Colorectal Cancer in Octogenarians: Results of Treatment, a Descriptive Clinical Study [PDF]
Iranian Journal of Colorectal Research, 2016 Background: Colorectal cancers (CRCs) often occur in octogenarians. However, data on treatment and survival are sparse.Objectives: Octogenarians were studied in order to gain data on treatment, outcomes, and survival related to CRC.Patients and Methods ...
Elmer van Eeghen +2 more
doaj
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane +16 more
wiley +1 more source
Risk and Secondary Prevention of Stroke Recurrence
Stroke, 2020 Supplemental Digital Content is available in the text. Background and Purpose: With recent advances in secondary prevention management, stroke recurrence rates may have changed substantially.
C. Flach +4 more
semanticscholar +1 more source
Recurrently Controlled Recurrent Networks
, 2018 Recurrent neural networks (RNNs) such as long short-term memory and gated recurrent units are pivotal building blocks across a broad spectrum of sequence modeling problems. This paper proposes a recurrently controlled recurrent network (RCRN) for expressive and powerful sequence encoding.
Tay, Yi, Tuan, Luu Anh, Hui, Siu Cheung
openaire +2 more sources
Recurrence without uniform recurrence [PDF]
Ergodic Theory and Dynamical Systems, 1987 AbstractWe construct a minimal homeomorphism of a compact space such that a sequence of its iterates converges pointwise to the identity but no sequence of its iterates converges uniformly.
openaire +2 more sources
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
Annals of Surgery, 2019 OBJECTIVES To establish an evidence-based cutoff to differentiate between early and late recurrence and to compare clinicopathologic risk factors between the two groups.
V. Groot +12 more
semanticscholar +1 more source