Results 81 to 90 of about 213,790 (291)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Sliding Recurrence Analysis and its Application of Gear Vibration Signal

Jixie chuandong, 2015
According to the recurrence plot analysis to the gear vibration signal,it is found that there are obvious difference between the gear condition and the driver system characteristics represented by recurrence plots.If the recurrence plots are regarded as ...
Xiao Han, Lv Yong
doaj  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Software Corrections of Vocal Disorders

, 2001
We discuss how vocal disorders can be post-corrected via a simple nonlinear noise reduction scheme. This work is motivated by the need of a better understanding of voice dysfunctions.
Manfredi, Claudia, Matassini, Lorenzo
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Complex Network Approach for Recurrence Analysis of Time Series

, 2009
We propose a novel approach for analysing time series using complex network theory. We identify the recurrence matrix calculated from time series with the adjacency matrix of a complex network, and apply measures for the characterisation of complex ...
Albert, Arenas, Bandt, Berger, Bigdeli, Boccaletti, Castellini, Collet, deMenocal, Donges, Donner, Facchini, Giuliani, John, Jonathan F. Donges, Jürgen Kurths, Kantz, Kurths, Kyrtsou, Lacasa, Mandelbrot, Marwan, Marwan, Marwan, Marwan, Marwan, McClymont, Mudelsee, Newman, Ngamga, Nichols, Norbert Marwan, Oblow, Packard, Proulx, Ravelo, Reik V. Donner, Robinson, Romano, Romano, Romano, Schinkel, Schinkel, Sen, Strogatz, Theiler, Thiel, Tiedemann, Trauth, Trulla, Wackerbauer, Watts, West, Wolf, Xu, Yang, Yong Zou, Zbilut, Zhang, Zhang   +59 more
core   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

A Nonlinear Method to Identify Seizure Dynamic Trajectory Based on Variance of Recurrence Rate in Human Epilepsy Patients Using EEG

Journal of Medical Signals and Sensors
Background: Surgery is a well-established treatment for drug-resistant epilepsy, but outcomes are often suboptimal, especially when no lesion is visible on preoperative imaging.
Morteza Farahi, Seyed Saman Sajadi, Fateme Karbasi, Seyed Sohrab Hashemi Fesharaki, Jafar Mehvari Habibabadi, Mohsen Reza Haidari, Amir Homayoun Jafari   +6 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Two Dimensional Directed Lattice Walks with Boundaries

, 2007
We present general algorithms (fully implemented in Maple) for calculations of various quantities related to constrained directed walks for a general set of steps on the square lattice in two dimensions.
Ayyer, Arvind, Zeilberger, Doron
core   +3 more sources