Results 81 to 90 of about 175,685 (330)
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Transitions and multistability in macroevolutionary dynamics of large mammals [PDF]
Acta Palaeontologica PolonicaOn multi-million-year timescales, the climate system of the Earth exhibits complex wandering behaviour. We investigate the evolutionary impacts of long-term climate change by analysing the dynamics of Cenozoic mammal evolution, looking for the presence ...
Simona Bekeraitė +4 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Recurrence plots of sunspots, solar flux and irradiance
, 2008 The paper shows the recurrence and cross recurrence plots of three time series, concerning data of the solar activity. The data are the sunspot number and the values of solar radio flux at 10.7 cm and of solar total irradiance, which are known as highly ...
Sparavigna, Amelia
core
Early warning of large volatilities based on recurrence interval analysis in Chinese stock markets
, 2015 Being able to forcast extreme volatility is a central issue in financial risk management. We present a large volatility predicting method based on the distribution of recurrence intervals between volatilities exceeding a certain threshold $Q$ for a fixed
Canabarro, Askery A. +4 more
core +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Identification of the nature of dynamical systems with recurrence plots and convolution neural networks: A preliminary test [PDF]
, 2021 Daniel Han +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Forecasting abrupt changes in foreign exchange markets: method using dynamical network marker
New Journal of Physics, 2014 We apply the idea of dynamical network markers (Chen et al 2012 Sci. Rep. http://dx.doi.org/10.1038/srep00342 ) to foreign exchange markets so that early warning signals can be provided for any abrupt changes.
Shunsuke Oya +2 more
doaj +1 more source
, 2016 Recurrence in the phase space of complex systems is a well-studied phenomenon, which has provided deep insights into the nonlinear dynamics of such systems.
Donner, Reik V. +3 more
core +1 more source